Timeseries analyses for MyConnectome dataset

Code available at: https://github.com/poldrack/myconnectome/blob/master/myconnectome/timeseries/timeseries_analyses.Rmd

This notebook runs all of the timeseries analyses presented in the MyConnectome paper. The tables list all tests that survived at FDR-corrected p < 0.1, correcting within each set of tests.

The variables listed in each table are:

Behavioral variables vs. each other:

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
1 panas.positive panas.negative -0.5268955 -5.375637 0.0000001 0.0000000 1.0000000 2 1 81 0.0000072
2 panas.positive panas.fatigue -0.5202793 -5.512736 0.0000000 0.0000000 1.0000000 2 1 81 0.0000072
10 panas.positive prevevening.Guthealth -0.4146208 -3.866145 0.0001106 0.0000000 1.0000000 1 1 72 0.0060023
20 panas.negative panas.positive -0.5268955 -5.378265 0.0000001 0.0000000 1.0000000 2 1 81 0.0000072
39 panas.fatigue panas.positive -0.5202793 -5.483054 0.0000000 0.0000000 1.0000000 1 1 81 0.0000072
49 panas.fatigue prevevening.Psoriasisseverity -0.3106464 -3.100385 0.0019327 0.0000000 1.0000000 2 1 72 0.0564942
52 panas.fatigue TuesThurs -0.3951684 -3.725476 0.0001949 0.0000000 1.0000000 1 1 75 0.0082311
85 afterscan.diastolic prevevening.Alcohol 0.2886855 3.401131 0.0006711 0.0000000 1.0000000 3 1 82 0.0255009
87 afterscan.diastolic prevevening.Psoriasisseverity 0.0215942 2.937826 0.0033052 0.0000000 1.0000000 3 1 82 0.0837323
152 morning.Sleepquality zeo.zq 0.4595645 4.679181 0.0000029 0.1267829 0.8991122 1 1 56 0.0002189
191 prevevening.Guthealth panas.positive -0.4146208 -3.143081 0.0016718 0.0000000 1.0000000 2 1 72 0.0529401
214 prevevening.Psoriasisseverity afterscan.diastolic 0.0215942 3.255288 0.0011328 -0.1410245 0.8878506 2 1 82 0.0391322
221 prevevening.Psoriasisseverity prevevening.Stress 0.3131546 2.991185 0.0027790 0.0000000 1.0000000 3 1 83 0.0754291
240 prevevening.Stress prevevening.Psoriasisseverity 0.3131546 2.904503 0.0036784 0.0000000 1.0000000 3 1 83 0.0873611
269 TuesThurs panas.fatigue -0.3951684 -3.725476 0.0001949 0.0000000 1.0000000 1 1 75 0.0082311
369 zeo.zq morning.Sleepquality 0.4595645 4.097944 0.0000417 0.0000000 1.0000000 2 1 56 0.0026400

Within-module connectivity vs. behavior

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
1 1:Default panas.positive 0.2914215 3.296490 0.0009790 0.0000000 1.0000000 2 1 74 0.0156642
9 1:Default morning.Soreness -0.0741661 -3.055430 0.0022474 0.1260017 0.8997306 1 1 82 0.0269686
31 2:Visual_2 prevevening.Guthealth 0.2934307 2.775522 0.0055113 0.0000000 1.0000000 2 1 74 0.0578411
45 3:Fronto_Parietal afterscan.diastolic 0.0844883 3.489985 0.0004830 -0.0095651 0.9923683 1 1 83 0.0089178
60 3:Fronto_Parietal zeo.zq 0.3775583 4.035721 0.0000544 0.1718778 0.8635336 1 1 51 0.0021682
64 4.5:Visual_1 afterscan.Anxietyduringscan -0.3361618 -5.395426 0.0000001 -0.1611445 0.8719796 1 1 83 0.0000082
67 4.5:Visual_1 afterscan.systolic 0.0851007 2.560810 0.0104429 0.0035726 0.9971495 1 1 83 0.0928253
75 4.5:Visual_1 TuesThurs -0.4428375 -4.190930 0.0000278 0.0000000 1.0000000 1 1 72 0.0016669
83 5:Dorsal_Attention panas.fatigue -0.4355790 -5.179027 0.0000002 0.0000000 1.0000000 2 1 74 0.0000178
86 5:Dorsal_Attention afterscan.pulse 0.3092516 4.020806 0.0000580 0.0000000 1.0000000 2 1 78 0.0021682
89 5:Dorsal_Attention morning.Soreness -0.0570209 -3.189782 0.0014238 0.1222791 0.9026780 1 1 82 0.0189840
95 5:Dorsal_Attention TuesThurs 0.3910352 3.605092 0.0003120 0.0000000 1.0000000 1 1 72 0.0068082
120 7:Ventral_Attention zeo.zq 0.2695478 3.643967 0.0002685 0.0690746 0.9449302 1 1 51 0.0064432
129 8:Salience morning.Soreness -0.1401288 -2.931377 0.0033746 0.1152790 0.9082240 1 1 82 0.0385672
145 9:Cingulo_opercular afterscan.diastolic 0.2866255 2.652949 0.0079792 -0.0007721 0.9993839 1 1 83 0.0766002
159 9:Cingulo_opercular email.LIWCposemo -0.2726701 -2.589892 0.0096006 0.0000000 1.0000000 2 1 83 0.0886209
161 10:Somatomotor panas.positive -0.3445522 -3.157276 0.0015925 0.0000000 1.0000000 1 1 74 0.0201159
163 10:Somatomotor panas.fatigue 0.4189055 4.000382 0.0000632 0.0000000 1.0000000 2 1 74 0.0021682
164 10:Somatomotor afterscan.Anxietyduringscan -0.2237771 -3.274654 0.0010579 -0.1207736 0.9038704 1 1 83 0.0158687
166 10:Somatomotor afterscan.pulse -0.3401615 -3.871196 0.0001083 0.0000000 1.0000000 2 1 78 0.0032491
171 10:Somatomotor prevevening.Guthealth 0.2789856 2.721323 0.0065021 0.0000000 1.0000000 2 1 74 0.0650212
175 10:Somatomotor TuesThurs -0.6227187 -6.753102 0.0000000 0.0000000 1.0000000 1 1 72 0.0000000
190 11.5:Fronto_Parietal_2 prevevening.Alcohol 0.0651428 2.773651 0.0055431 0.0533580 0.9574467 1 1 74 0.0578411
200 11.5:Fronto_Parietal_2 zeo.zq -0.1777446 -3.538258 0.0004028 0.1736109 0.8621713 1 1 51 0.0080555
207 15:Medial_Parietal afterscan.systolic -0.0987387 -3.225866 0.0012559 -0.0093672 0.9925261 1 1 83 0.0177306
209 15:Medial_Parietal morning.Soreness 0.2064493 3.344336 0.0008248 0.1673715 0.8670778 1 1 82 0.0141394
216 15:Medial_Parietal temp.mean 0.1460086 3.754885 0.0001734 0.0000000 1.0000000 2 1 84 0.0046246

Between-module connectivity vs. behavior

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
33 1_DMN-3_Frontoparietal_1 prevevening.Stress -0.4254681 -3.721923 0.0001977 0.0000000 1.0000000 2 1 74 0.0089815
40 1_DMN-3_Frontoparietal_1 zeo.zq -0.0560923 -2.938899 0.0032938 0.0618561 0.9506775 1 1 51 0.0748228
43 1_DMN-4.5_Visual_1 panas.fatigue -0.3135700 -2.859189 0.0042473 0.0000000 1.0000000 2 1 74 0.0836772
47 1_DMN-4.5_Visual_1 afterscan.systolic -0.1008902 -2.818128 0.0048305 -0.0442061 0.9647401 1 1 83 0.0910887
49 1_DMN-4.5_Visual_1 morning.Soreness -0.3679234 -4.635857 0.0000036 0.0742224 0.9408335 1 1 82 0.0004692
64 1_DMN-5_Dorsal_Attention afterscan.Anxietyduringscan -0.2695397 -3.086618 0.0020245 -0.1284638 0.8977819 1 1 83 0.0524996
75 1_DMN-5_Dorsal_Attention TuesThurs -0.3349417 -3.016295 0.0025588 0.0000000 1.0000000 1 1 72 0.0631675
92 1_DMN-7_Ventral_Attention prevevening.Psoriasisseverity 0.2930649 2.863194 0.0041939 0.0000000 1.0000000 2 1 74 0.0836772
160 1_DMN-10_Somatomotor zeo.zq -0.2725396 -3.022423 0.0025076 0.1476539 0.8826160 1 1 51 0.0631675
220 1_DMN-16_Parieto_occipital zeo.zq 0.1180927 3.104480 0.0019061 0.0733367 0.9415382 1 1 51 0.0513490
243 2_Visual_2-4.5_Visual_1 panas.fatigue 0.4003380 5.101679 0.0000003 -0.1190398 0.9052439 1 1 74 0.0000889
263 2_Visual_2-5_Dorsal_Attention panas.fatigue 0.4963281 5.064383 0.0000004 0.0000000 1.0000000 2 1 74 0.0000901
272 2_Visual_2-5_Dorsal_Attention prevevening.Psoriasisseverity -0.2995787 -2.831264 0.0046364 0.0000000 1.0000000 2 1 74 0.0900014
301 2_Visual_2-8_Salience panas.positive 0.3210563 2.916212 0.0035431 0.0000000 1.0000000 1 1 74 0.0777556
303 2_Visual_2-8_Salience panas.fatigue -0.4342972 -4.147521 0.0000336 0.0000000 1.0000000 1 1 74 0.0029576
315 2_Visual_2-8_Salience TuesThurs 0.4303531 4.045444 0.0000522 0.0000000 1.0000000 1 1 72 0.0033822
332 2_Visual_2-9_Cingulo_opercular prevevening.Psoriasisseverity 0.2292643 2.880234 0.0039738 0.0000000 1.0000000 2 1 74 0.0806986
351 2_Visual_2-10_Somatomotor prevevening.Guthealth 0.2683605 2.789901 0.0052724 0.0000000 1.0000000 2 1 74 0.0966611
355 2_Visual_2-10_Somatomotor TuesThurs -0.4362250 -4.113505 0.0000390 0.0000000 1.0000000 1 1 72 0.0030847
371 2_Visual_2-11.5_Frontoparietal_2 prevevening.Guthealth -0.3204864 -3.941236 0.0000811 0.0000000 1.0000000 2 1 74 0.0042801
383 2_Visual_2-15_Medial_Parietal panas.fatigue -0.5356196 -5.447163 0.0000001 0.0000000 1.0000000 2 1 74 0.0000338
395 2_Visual_2-15_Medial_Parietal TuesThurs 0.4142180 3.861611 0.0001126 0.0000000 1.0000000 1 1 72 0.0057187
399 2_Visual_2-15_Medial_Parietal email.LIWCposemo -0.2814394 -2.910460 0.0036090 0.0000000 1.0000000 2 1 83 0.0777556
423 3_Frontoparietal_1-4.5_Visual_1 panas.fatigue -0.4263806 -4.054928 0.0000501 0.0000000 1.0000000 1 1 74 0.0033822
443 3_Frontoparietal_1-5_Dorsal_Attention panas.fatigue -0.3131784 -4.003396 0.0000624 0.0000000 1.0000000 2 1 74 0.0035900
480 3_Frontoparietal_1-7_Ventral_Attention zeo.zq -0.3727057 -3.493953 0.0004759 0.1181978 0.9059110 1 1 51 0.0184771
505 3_Frontoparietal_1-9_Cingulo_opercular afterscan.diastolic -0.1537137 -2.802895 0.0050646 -0.0001074 0.9999143 1 1 83 0.0941590
524 3_Frontoparietal_1-10_Somatomotor afterscan.Anxietyduringscan 0.1057109 3.426003 0.0006125 -0.1527203 0.8786189 1 1 83 0.0216451
563 3_Frontoparietal_1-15_Medial_Parietal panas.fatigue 0.3181056 2.884026 0.0039263 0.0000000 1.0000000 2 1 74 0.0806986
609 4.5_Visual_1-5_Dorsal_Attention morning.Soreness 0.2001858 3.086043 0.0020284 0.0839967 0.9330590 1 1 82 0.0524996
647 4.5_Visual_1-8_Salience afterscan.systolic -0.0138751 -3.759877 0.0001700 -0.0605783 0.9516950 1 1 83 0.0080142
661 4.5_Visual_1-9_Cingulo_opercular panas.positive -0.3963658 -3.713855 0.0002041 0.0000000 1.0000000 1 1 74 0.0089815
663 4.5_Visual_1-9_Cingulo_opercular panas.fatigue 0.6206305 6.808872 0.0000000 0.0000000 1.0000000 1 1 74 0.0000000
683 4.5_Visual_1-10_Somatomotor panas.fatigue 0.3392447 3.191350 0.0014161 0.0000000 1.0000000 2 1 74 0.0424829
689 4.5_Visual_1-10_Somatomotor morning.Soreness 0.1248107 2.998883 0.0027097 0.1195656 0.9048272 1 1 82 0.0650331
710 4.5_Visual_1-11.5_Frontoparietal_2 prevevening.Alcohol -0.1929241 -5.242406 0.0000002 -0.0872247 0.9304929 1 1 74 0.0000523
727 4.5_Visual_1-15_Medial_Parietal afterscan.systolic 0.0225854 -4.090794 0.0000430 -0.0553480 0.9558612 1 1 83 0.0031526
730 4.5_Visual_1-15_Medial_Parietal prevevening.Alcohol -0.0316363 3.174117 0.0015029 0.0775710 0.9381693 1 1 74 0.0440860
744 4.5_Visual_1-16_Parieto_occipital afterscan.Anxietyduringscan -0.0057357 -4.160823 0.0000317 -0.2007257 0.8409131 1 1 83 0.0029576
761 5_Dorsal_Attention-7_Ventral_Attention panas.positive -0.3487259 -3.200780 0.0013706 0.0000000 1.0000000 1 1 74 0.0420731
763 5_Dorsal_Attention-7_Ventral_Attention panas.fatigue 0.4464096 4.776547 0.0000018 0.0000000 1.0000000 2 1 74 0.0002942
766 5_Dorsal_Attention-7_Ventral_Attention afterscan.pulse -0.2772191 -3.156675 0.0015958 0.0000000 1.0000000 2 1 78 0.0457923
772 5_Dorsal_Attention-7_Ventral_Attention prevevening.Psoriasisseverity -0.2732652 -3.453480 0.0005534 0.0000000 1.0000000 2 1 74 0.0202915
804 5_Dorsal_Attention-9_Cingulo_opercular afterscan.Anxietyduringscan 0.2659478 2.898206 0.0037530 -0.1406749 0.8881267 1 1 83 0.0786352
807 5_Dorsal_Attention-9_Cingulo_opercular afterscan.systolic -0.0335143 -4.412438 0.0000102 -0.0079726 0.9936388 1 1 83 0.0011243
823 5_Dorsal_Attention-10_Somatomotor panas.fatigue 0.4007643 3.762903 0.0001680 0.0000000 1.0000000 1 1 74 0.0080142
832 5_Dorsal_Attention-10_Somatomotor prevevening.Psoriasisseverity -0.2571076 -2.774868 0.0055224 0.0000000 1.0000000 2 1 74 0.0998572
843 5_Dorsal_Attention-11.5_Frontoparietal_2 panas.fatigue -0.4092602 -4.038441 0.0000538 0.0000000 1.0000000 2 1 74 0.0033822
880 5_Dorsal_Attention-15_Medial_Parietal zeo.zq -0.1645181 -2.824523 0.0047351 0.0958236 0.9236607 1 1 51 0.0905846
889 5_Dorsal_Attention-16_Parieto_occipital morning.Soreness 0.0246497 3.013313 0.0025841 0.1162737 0.9074356 1 1 82 0.0631675
895 5_Dorsal_Attention-16_Parieto_occipital TuesThurs -0.3240754 -2.906741 0.0036522 0.0000000 1.0000000 1 1 72 0.0777556
903 7_Ventral_Attention-8_Salience panas.fatigue -0.4238463 -4.254336 0.0000210 0.0000000 1.0000000 2 1 74 0.0021290
906 7_Ventral_Attention-8_Salience afterscan.pulse 0.3334258 3.992892 0.0000653 0.0000000 1.0000000 2 1 78 0.0035900
946 7_Ventral_Attention-10_Somatomotor afterscan.pulse -0.3088051 -3.115852 0.0018341 0.0000000 1.0000000 2 1 78 0.0508938
981 7_Ventral_Attention-15_Medial_Parietal panas.positive 0.3509604 3.224159 0.0012634 0.0000000 1.0000000 1 1 74 0.0397078
983 7_Ventral_Attention-15_Medial_Parietal panas.fatigue -0.4146141 -3.997640 0.0000640 0.0000000 1.0000000 2 1 74 0.0035900
986 7_Ventral_Attention-15_Medial_Parietal afterscan.pulse 0.2971878 3.614726 0.0003007 0.0000000 1.0000000 2 1 78 0.0126094
987 7_Ventral_Attention-15_Medial_Parietal afterscan.systolic 0.1715132 2.934175 0.0033444 -0.0015375 0.9987733 1 1 83 0.0748228
999 7_Ventral_Attention-15_Medial_Parietal email.LIWCposemo -0.3085221 -3.267979 0.0010832 0.0000000 1.0000000 2 1 83 0.0357451
1007 7_Ventral_Attention-16_Parieto_occipital afterscan.systolic 0.1137070 3.610435 0.0003057 0.0228092 0.9818025 1 1 83 0.0126094
1027 8_Salience-9_Cingulo_opercular afterscan.systolic 0.0624348 2.970015 0.0029779 0.0019886 0.9984133 1 1 83 0.0701923
1041 8_Salience-10_Somatomotor panas.positive 0.3677395 3.401777 0.0006695 0.0000000 1.0000000 1 1 74 0.0226597
1043 8_Salience-10_Somatomotor panas.fatigue -0.4650392 -4.518759 0.0000062 0.0000000 1.0000000 1 1 74 0.0007464
1055 8_Salience-10_Somatomotor TuesThurs 0.4826528 4.676163 0.0000029 0.0000000 1.0000000 1 1 72 0.0004287
1092 8_Salience-15_Medial_Parietal prevevening.Psoriasisseverity -0.2854419 -3.421347 0.0006231 0.0000000 1.0000000 2 1 74 0.0216451
1126 9_Cingulo_opercular-10_Somatomotor afterscan.pulse 0.4166746 3.459054 0.0005421 0.0000000 1.0000000 2 1 78 0.0202915
1160 9_Cingulo_opercular-11.5_Frontoparietal_2 zeo.zq -0.1090115 -3.113203 0.0018507 0.1417241 0.8872979 1 1 51 0.0508938
1165 9_Cingulo_opercular-15_Medial_Parietal afterscan.diastolic -0.0740174 -3.250967 0.0011501 -0.0127096 0.9898595 1 1 83 0.0370287
1201 10_Somatomotor-11.5_Frontoparietal_2 panas.positive 0.3247467 2.953658 0.0031403 0.0000000 1.0000000 1 1 74 0.0727231
1215 10_Somatomotor-11.5_Frontoparietal_2 TuesThurs 0.4358435 4.109064 0.0000397 0.0000000 1.0000000 1 1 72 0.0030847
1223 10_Somatomotor-15_Medial_Parietal panas.fatigue -0.4873376 -4.785237 0.0000017 0.0000000 1.0000000 2 1 74 0.0002942
1235 10_Somatomotor-15_Medial_Parietal TuesThurs 0.5323897 5.336649 0.0000001 0.0000000 1.0000000 1 1 72 0.0000417
1292 11.5_Frontoparietal_2-16_Parieto_occipital prevevening.Psoriasisseverity 0.4065335 3.505880 0.0004551 0.0000000 1.0000000 2 1 74 0.0182040

Network measures vs. behavior

[1] “no significant results”

Participation index vs. behavior

[1] “skipping printout”

Behavior vs. RNA-seq:

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
50 ME3:Cell Cycle prevevening.Psoriasisseverity -0.5723688 -4.391812 0.0000112 0 1 1 1 40 0.0134555
88 ME5:ncRNA processing prevevening.Psoriasisseverity -0.5405435 -4.178832 0.0000293 0 1 1 1 40 0.0175366
145 ME8:no enrichment prevevening.Psoriasisseverity -0.5165896 -3.677173 0.0002358 0 1 2 1 40 0.0470488
175 ME10:Processing of Capped Intron-Containing Pre-mRNA afterscan.Anxietyduringscan 0.3663957 3.309689 0.0009340 0 1 3 3 47 0.0931661
335 ME18:no enrichment prevevening.Psoriasisseverity -0.5135311 -3.501429 0.0004628 0 1 2 1 40 0.0574550
430 ME23:Signaling by Wnt prevevening.Psoriasisseverity 0.5142890 3.752806 0.0001749 0 1 1 1 40 0.0418630
563 ME30:Signalling by NGF prevevening.Psoriasisseverity -0.3790282 -3.510199 0.0004478 0 1 2 1 40 0.0574550
620 ME33:no enrichment prevevening.Psoriasisseverity -0.5152493 -3.801792 0.0001437 0 1 1 1 40 0.0418630
862 ME46:no enrichment afterscan.systolic -0.3363988 -3.491681 0.0004800 0 1 1 2 47 0.0574550
924 ME49:no enrichment prevevening.Psoriasisseverity -0.3569641 -3.337865 0.0008442 0 1 3 1 40 0.0918694
943 ME50:transition metal ion binding prevevening.Psoriasisseverity 0.4330195 3.793945 0.0001483 0 1 3 1 40 0.0418630
1114 ME59:Telomere Maintenance prevevening.Psoriasisseverity -0.4883222 -3.534635 0.0004083 0 1 1 1 40 0.0574550

Within-module connectivity vs. RNA-seq

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
24 ME2:HIV Infection 16:Parieto_Occipital 0.4849182 3.471734 0.0005171 0.000000 1.0000000 1 1 39 0.0781868
120 ME10:Processing of Capped Intron-Containing Pre-mRNA 16:Parieto_Occipital -0.5480427 -4.081715 0.0000447 0.000000 1.0000000 1 1 39 0.0337967
179 ME15:no enrichment 15:Medial_Parietal -0.5354437 -3.702600 0.0002134 0.000000 1.0000000 1 1 39 0.0739286
212 ME18:no enrichment 9:Cingulo_opercular 0.4950522 3.330520 0.0008668 0.000000 1.0000000 1 1 39 0.0819164
396 ME33:no enrichment 16:Parieto_Occipital -0.4963379 -3.583476 0.0003391 0.000000 1.0000000 1 1 39 0.0739286
477 ME40:no enrichment 10:Somatomotor 0.1801061 3.335527 0.0008514 2.313906 0.0206729 4 2 39 0.0819164
524 ME44:no enrichment 9:Cingulo_opercular 0.4978663 3.545980 0.0003912 0.000000 1.0000000 1 1 39 0.0739286
600 ME50:transition metal ion binding 16:Parieto_Occipital 0.4734006 3.353250 0.0007987 0.000000 1.0000000 1 1 39 0.0819164

Between-module connectivity vs. RNA-seq

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
31 ME1:Hemostasis 4.5_Visual_1-5_Dorsal_Attention 0.4963249 3.570337 0.0003565 0 1 1 1 39 0.0354287
87 ME2:HIV Infection 2_Visual_2-16_Parieto_occipital -0.5228213 -3.638990 0.0002737 0 1 1 2 39 0.0343383
99 ME2:HIV Infection 4.5_Visual_1-8_Salience 0.4308677 2.993184 0.0027608 0 1 1 1 39 0.0889886
129 ME2:HIV Infection 10_Somatomotor-16_Parieto_occipital -0.5484627 -4.102872 0.0000408 0 1 1 1 39 0.0121192
131 ME2:HIV Infection 11.5_Frontoparietal_2-16_Parieto_occipital 0.5155788 3.750173 0.0001767 0 1 1 1 39 0.0282604
139 ME3:Cell Cycle 1_DMN-9_Cingulo_opercular -0.5016679 -3.621607 0.0002928 0 1 1 1 39 0.0343383
153 ME3:Cell Cycle 2_Visual_2-16_Parieto_occipital 0.5239370 3.628335 0.0002853 0 1 1 2 39 0.0343383
195 ME3:Cell Cycle 10_Somatomotor-16_Parieto_occipital 0.4408540 3.068716 0.0021498 0 1 1 1 39 0.0813012
205 ME4:transcription 1_DMN-9_Cingulo_opercular -0.4883290 -3.494612 0.0004748 0 1 1 1 39 0.0398455
219 ME4:transcription 2_Visual_2-16_Parieto_occipital 0.4461898 3.114949 0.0018398 0 1 1 1 39 0.0788636
231 ME4:transcription 4.5_Visual_1-8_Salience -0.4538917 -3.190900 0.0014183 0 1 1 1 39 0.0711828
366 ME6:Signaling in Immune system 4.5_Visual_1-11.5_Frontoparietal_2 -0.3271277 -2.986479 0.0028221 0 1 2 2 39 0.0902640
382 ME6:Signaling in Immune system 8_Salience-9_Cingulo_opercular 0.4591064 3.267646 0.0010845 0 1 1 1 39 0.0597394
403 ME7:chromatin modification 1_DMN-9_Cingulo_opercular -0.4470948 -3.121456 0.0017996 0 1 1 1 39 0.0779448
408 ME7:chromatin modification 2_Visual_2-3_Frontoparietal_1 -0.4072892 -3.514755 0.0004402 0 1 2 2 39 0.0387914
423 ME7:chromatin modification 3_Frontoparietal_1-10_Somatomotor -0.4954733 -4.485074 0.0000073 0 1 1 2 39 0.0030307
469 ME8:no enrichment 1_DMN-9_Cingulo_opercular -0.4864523 -3.477008 0.0005070 0 1 1 1 39 0.0405439
483 ME8:no enrichment 2_Visual_2-16_Parieto_occipital 0.4976097 3.906595 0.0000936 0 1 1 2 39 0.0185340
525 ME8:no enrichment 10_Somatomotor-16_Parieto_occipital 0.5010912 3.617640 0.0002973 0 1 1 1 39 0.0343383
527 ME8:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.5067128 -3.624541 0.0002895 0 1 1 1 39 0.0343383
540 ME9:DNA repair 2_Visual_2-3_Frontoparietal_1 -0.1999947 -3.338595 0.0008420 0 1 2 2 39 0.0510353
543 ME9:DNA repair 2_Visual_2-7_Ventral_Attention 0.3492186 3.005520 0.0026513 0 1 1 2 39 0.0889886
552 ME9:DNA repair 3_Frontoparietal_1-7_Ventral_Attention -0.4535889 -3.367689 0.0007580 0 1 1 3 39 0.0489821
576 ME9:DNA repair 7_Ventral_Attention-10_Somatomotor 0.3377602 3.186906 0.0014380 0 1 1 2 39 0.0711828
606 ME10:Processing of Capped Intron-Containing Pre-mRNA 2_Visual_2-3_Frontoparietal_1 -0.2932006 -3.326770 0.0008786 0 1 2 2 39 0.0521881
618 ME10:Processing of Capped Intron-Containing Pre-mRNA 3_Frontoparietal_1-7_Ventral_Attention -0.4458622 -3.085342 0.0020332 0 1 1 1 39 0.0813012
621 ME10:Processing of Capped Intron-Containing Pre-mRNA 3_Frontoparietal_1-10_Somatomotor -0.4272291 -4.528381 0.0000059 0 1 1 2 39 0.0027460
642 ME10:Processing of Capped Intron-Containing Pre-mRNA 7_Ventral_Attention-10_Somatomotor 0.3060042 3.243549 0.0011805 0 1 4 1 39 0.0621335
659 ME10:Processing of Capped Intron-Containing Pre-mRNA 11.5_Frontoparietal_2-16_Parieto_occipital -0.5314482 -3.918246 0.0000892 0 1 1 1 39 0.0185340
675 ME11:Circadian clock system 2_Visual_2-7_Ventral_Attention -0.2617655 -3.134524 0.0017213 0 1 1 1 39 0.0769601
687 ME11:Circadian clock system 3_Frontoparietal_1-10_Somatomotor 0.4323239 2.994125 0.0027523 0 1 1 1 39 0.0889886
708 ME11:Circadian clock system 7_Ventral_Attention-10_Somatomotor -0.2961447 -3.569352 0.0003579 0 1 1 1 39 0.0354287
753 ME12:zinc ion binding 3_Frontoparietal_1-10_Somatomotor 0.4940003 3.548201 0.0003879 0 1 1 1 39 0.0366539
855 ME13:Gene Expression 10_Somatomotor-16_Parieto_occipital -0.4678004 -3.306900 0.0009433 0 1 1 1 39 0.0544782
865 ME14:nucleotide binding 1_DMN-9_Cingulo_opercular -0.4500495 -3.147302 0.0016478 0 1 1 1 39 0.0752940
878 ME14:nucleotide binding 2_Visual_2-15_Medial_Parietal -0.4187839 -3.068575 0.0021508 0 1 2 1 39 0.0813012
879 ME14:nucleotide binding 2_Visual_2-16_Parieto_occipital 0.4418733 3.047428 0.0023081 0 1 1 2 39 0.0834525
885 ME14:nucleotide binding 3_Frontoparietal_1-10_Somatomotor -0.3486330 -3.560527 0.0003701 0 1 1 2 39 0.0357889
923 ME14:nucleotide binding 11.5_Frontoparietal_2-16_Parieto_occipital -0.4631734 -3.255354 0.0011325 0 1 1 1 39 0.0611556
1002 ME16:no enrichment 2_Visual_2-3_Frontoparietal_1 0.2850812 3.034612 0.0024085 0 1 2 2 39 0.0863307
1011 ME16:no enrichment 2_Visual_2-16_Parieto_occipital -0.4070998 -3.078378 0.0020813 0 1 1 2 39 0.0813012
1017 ME16:no enrichment 3_Frontoparietal_1-10_Somatomotor 0.5137315 3.739428 0.0001844 0 1 1 1 39 0.0284037
1053 ME16:no enrichment 10_Somatomotor-16_Parieto_occipital -0.4842640 -3.434127 0.0005945 0 1 1 1 39 0.0431869
1055 ME16:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital 0.4828148 3.441427 0.0005787 0 1 1 1 39 0.0431869
1092 ME17:no enrichment 4.5_Visual_1-11.5_Frontoparietal_2 -0.3826746 -3.161858 0.0015677 0 1 2 1 39 0.0732397
1129 ME18:no enrichment 1_DMN-9_Cingulo_opercular -0.4388472 -3.049978 0.0022886 0 1 1 1 39 0.0834525
1143 ME18:no enrichment 2_Visual_2-16_Parieto_occipital 0.5049805 3.593616 0.0003261 0 1 1 2 39 0.0347695
1158 ME18:no enrichment 4.5_Visual_1-11.5_Frontoparietal_2 -0.4784665 -4.177813 0.0000294 0 1 2 1 39 0.0094139
1185 ME18:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4755088 3.381820 0.0007201 0 1 1 1 39 0.0482913
1187 ME18:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.4430691 -3.057285 0.0022335 0 1 1 1 39 0.0829194
1279 ME20:immune response 3_Frontoparietal_1-8_Salience -0.4915127 -3.524622 0.0004241 0 1 1 1 39 0.0383338
1281 ME20:immune response 3_Frontoparietal_1-10_Somatomotor 0.4521477 3.165735 0.0015469 0 1 1 1 39 0.0730917
1306 ME20:immune response 8_Salience-9_Cingulo_opercular 0.4415318 3.076621 0.0020936 0 1 1 1 39 0.0813012
1310 ME20:immune response 8_Salience-16_Parieto_occipital 0.4266831 2.946292 0.0032161 0 1 1 1 39 0.0979413
1332 ME21:negative regulation of macromolecule metabolic process 2_Visual_2-3_Frontoparietal_1 -0.4191820 -5.231156 0.0000002 0 1 4 1 39 0.0002335
1344 ME21:negative regulation of macromolecule metabolic process 3_Frontoparietal_1-7_Ventral_Attention -0.4266756 -2.996714 0.0027291 0 1 1 1 39 0.0889886
1348 ME21:negative regulation of macromolecule metabolic process 3_Frontoparietal_1-11.5_Frontoparietal_2 0.4708513 3.414860 0.0006381 0 1 1 1 39 0.0442237
1438 ME22:no enrichment 8_Salience-9_Cingulo_opercular -0.3460171 -3.173273 0.0015073 0 1 3 3 39 0.0722071
1473 ME23:Signaling by Wnt 2_Visual_2-16_Parieto_occipital -0.4725038 -3.336991 0.0008469 0 1 1 1 39 0.0510353
1485 ME23:Signaling by Wnt 4.5_Visual_1-8_Salience 0.4839949 3.481310 0.0004990 0 1 1 1 39 0.0405439
1525 ME24:RNA processing 1_DMN-9_Cingulo_opercular -0.4291888 -2.967486 0.0030025 0 1 1 1 39 0.0941363
1604 ME25:RNA splicing 2_Visual_2-15_Medial_Parietal -0.4678758 -3.577843 0.0003464 0 1 2 1 39 0.0354287
1605 ME25:RNA splicing 2_Visual_2-16_Parieto_occipital 0.2521552 3.785437 0.0001534 0 1 4 1 39 0.0273589
1608 ME25:RNA splicing 3_Frontoparietal_1-7_Ventral_Attention -0.2237615 -3.016341 0.0025585 0 1 4 1 39 0.0883161
1626 ME25:RNA splicing 5_Dorsal_Attention-10_Somatomotor 0.2550641 4.994113 0.0000006 0 1 3 1 39 0.0004915
1628 ME25:RNA splicing 5_Dorsal_Attention-15_Medial_Parietal -0.4295539 -2.947085 0.0032078 0 1 1 1 39 0.0979413
1662 ME26:no enrichment 2_Visual_2-3_Frontoparietal_1 0.3171597 3.077613 0.0020867 0 1 2 2 39 0.0813012
1677 ME26:no enrichment 3_Frontoparietal_1-10_Somatomotor 0.4437348 3.092219 0.0019867 0 1 1 1 39 0.0813012
1796 ME28:no enrichment 2_Visual_2-5_Dorsal_Attention 0.4435064 3.206062 0.0013456 0 1 1 1 39 0.0699401
1935 ME30:Signalling by NGF 2_Visual_2-16_Parieto_occipital 0.4330067 4.057618 0.0000496 0 1 4 1 39 0.0137424
1950 ME30:Signalling by NGF 4.5_Visual_1-11.5_Frontoparietal_2 -0.3618308 -3.014970 0.0025700 0 1 1 2 39 0.0883161
1977 ME30:Signalling by NGF 10_Somatomotor-16_Parieto_occipital 0.5177992 3.778280 0.0001579 0 1 1 1 39 0.0273589
1979 ME30:Signalling by NGF 11.5_Frontoparietal_2-16_Parieto_occipital -0.4540696 -3.141002 0.0016837 0 1 1 1 39 0.0760962
1992 ME31:no enrichment 2_Visual_2-3_Frontoparietal_1 0.3412249 3.023901 0.0024954 0 1 4 1 39 0.0871916
2031 ME31:no enrichment 7_Ventral_Attention-16_Parieto_occipital -0.2302753 -5.558873 0.0000000 0 1 3 1 39 0.0000564
2133 ME33:no enrichment 2_Visual_2-16_Parieto_occipital 0.4580415 4.744165 0.0000021 0 1 2 2 39 0.0012436
2148 ME33:no enrichment 4.5_Visual_1-11.5_Frontoparietal_2 -0.3236803 -2.999372 0.0027054 0 1 4 1 39 0.0889886
2175 ME33:no enrichment 10_Somatomotor-16_Parieto_occipital 0.5391781 3.995015 0.0000647 0 1 1 1 39 0.0149434
2177 ME33:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.5119460 -3.671696 0.0002409 0 1 1 1 39 0.0343383
2226 ME34:no enrichment 7_Ventral_Attention-10_Somatomotor 0.2338549 3.621886 0.0002925 0 1 1 1 39 0.0343383
2246 ME35:modification-dependent macromolecule catabolic process 1_DMN-3_Frontoparietal_1 0.4570329 3.244607 0.0011761 0 1 1 1 39 0.0621335
2277 ME35:modification-dependent macromolecule catabolic process 4.5_Visual_1-8_Salience -0.4609318 -3.147990 0.0016440 0 1 1 1 39 0.0752940
2330 ME36:no enrichment 2_Visual_2-15_Medial_Parietal -0.4375908 -3.425908 0.0006127 0 1 1 2 39 0.0431869
2411 ME37:IFN alpha signaling pathway 4.5_Visual_1-10_Somatomotor 0.4259069 2.966603 0.0030111 0 1 1 1 39 0.0941363
2428 ME37:IFN alpha signaling pathway 8_Salience-9_Cingulo_opercular 0.4606894 3.265705 0.0010919 0 1 1 1 39 0.0597394
2475 ME38:no enrichment 4.5_Visual_1-8_Salience -0.2748192 -2.973300 0.0029462 0 1 3 1 39 0.0935125
2528 ME39:no enrichment 2_Visual_2-15_Medial_Parietal -0.4462453 -3.598647 0.0003199 0 1 2 1 39 0.0347695
2529 ME39:no enrichment 2_Visual_2-16_Parieto_occipital 0.4262056 3.080152 0.0020690 0 1 1 2 39 0.0813012
2571 ME39:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4640773 3.279330 0.0010405 0 1 1 1 39 0.0584671
2573 ME39:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.4424409 -3.073414 0.0021162 0 1 1 1 39 0.0813012
2595 ME40:no enrichment 2_Visual_2-16_Parieto_occipital 0.3181964 3.062785 0.0021929 0 1 1 2 39 0.0821439
2637 ME40:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4893342 3.510177 0.0004478 0 1 1 1 39 0.0387914
2816 ME43:no enrichment 5_Dorsal_Attention-15_Medial_Parietal -0.4365686 -3.025087 0.0024856 0 1 1 1 39 0.0871916
2837 ME43:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.4425864 -3.080135 0.0020691 0 1 1 1 39 0.0813012
2845 ME44:no enrichment 1_DMN-9_Cingulo_opercular -0.4809638 -3.425885 0.0006128 0 1 1 1 39 0.0431869
2859 ME44:no enrichment 2_Visual_2-16_Parieto_occipital 0.4733999 3.354324 0.0007956 0 1 1 1 39 0.0501222
2871 ME44:no enrichment 4.5_Visual_1-8_Salience -0.5061064 -3.648481 0.0002638 0 1 1 1 39 0.0343383
2874 ME44:no enrichment 4.5_Visual_1-11.5_Frontoparietal_2 -0.4425987 -3.073315 0.0021169 0 1 1 1 39 0.0813012
2913 ME45:no enrichment 1_DMN-11.5_Frontoparietal_2 -0.4413573 -2.945242 0.0032270 0 1 1 1 39 0.0979413
2925 ME45:no enrichment 2_Visual_2-16_Parieto_occipital 0.3527378 4.839772 0.0000013 0 1 3 1 39 0.0009008
2956 ME45:no enrichment 8_Salience-9_Cingulo_opercular -0.2885327 -4.599444 0.0000042 0 1 3 3 39 0.0022018
2962 ME45:no enrichment 9_Cingulo_opercular-11.5_Frontoparietal_2 0.4656193 3.088085 0.0020145 0 1 1 1 39 0.0813012
2967 ME45:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4381241 3.051165 0.0022796 0 1 1 1 39 0.0834525
2969 ME45:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.4014501 -3.124463 0.0017813 0 1 2 1 39 0.0779448
3063 ME47:no enrichment 3_Frontoparietal_1-10_Somatomotor 0.2863691 3.026185 0.0024766 0 1 1 2 39 0.0871916
3189 ME49:no enrichment 2_Visual_2-16_Parieto_occipital 0.3248207 3.129708 0.0017498 0 1 1 2 39 0.0774008
3231 ME49:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4855820 3.465331 0.0005296 0 1 1 1 39 0.0415470
3233 ME49:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital -0.4931544 -4.307277 0.0000165 0 1 1 2 39 0.0057954
3255 ME50:transition metal ion binding 2_Visual_2-16_Parieto_occipital -0.5170915 -3.787100 0.0001524 0 1 1 2 39 0.0273589
3259 ME50:transition metal ion binding 3_Frontoparietal_1-8_Salience -0.4236429 -3.372840 0.0007440 0 1 1 2 39 0.0489821
3261 ME50:transition metal ion binding 3_Frontoparietal_1-10_Somatomotor 0.4743420 3.364900 0.0007657 0 1 1 1 39 0.0489821
3290 ME50:transition metal ion binding 8_Salience-16_Parieto_occipital 0.4416312 2.998559 0.0027126 0 1 1 1 39 0.0889886
3297 ME50:transition metal ion binding 10_Somatomotor-16_Parieto_occipital -0.4815521 -3.429913 0.0006038 0 1 1 1 39 0.0431869
3299 ME50:transition metal ion binding 11.5_Frontoparietal_2-16_Parieto_occipital 0.4831791 3.446003 0.0005689 0 1 1 1 39 0.0431869
3386 ME52:protein catabolic process 2_Visual_2-15_Medial_Parietal 0.4247095 3.316236 0.0009124 0 1 2 1 39 0.0534325
3393 ME52:protein catabolic process 3_Frontoparietal_1-10_Somatomotor 0.3847191 5.127683 0.0000003 0 1 3 3 39 0.0003049
3570 ME55:IL 5 Signaling Pathway 1_DMN-8_Salience 0.4303023 3.002602 0.0026768 0 1 1 1 39 0.0889886
3597 ME55:IL 5 Signaling Pathway 4.5_Visual_1-8_Salience -0.4052070 -3.189169 0.0014268 0 1 1 2 39 0.0711828
3642 ME56:no enrichment 2_Visual_2-3_Frontoparietal_1 0.3956546 3.183288 0.0014561 0 1 2 2 39 0.0712303
3657 ME56:no enrichment 3_Frontoparietal_1-10_Somatomotor 0.5317670 3.921258 0.0000881 0 1 1 1 39 0.0185340
3717 ME57:no enrichment 2_Visual_2-16_Parieto_occipital 0.5401662 4.009571 0.0000608 0 1 1 1 39 0.0149434
3723 ME57:no enrichment 3_Frontoparietal_1-10_Somatomotor -0.4768934 -3.388309 0.0007032 0 1 1 1 39 0.0479363
3759 ME57:no enrichment 10_Somatomotor-16_Parieto_occipital 0.4442330 3.101933 0.0019226 0 1 1 1 39 0.0813012
3777 ME58:transcription 2_Visual_2-7_Ventral_Attention -0.0707032 -3.604541 0.0003127 0 1 4 1 39 0.0347695
3783 ME58:transcription 2_Visual_2-16_Parieto_occipital -0.1876969 -3.492153 0.0004791 0 1 4 1 39 0.0398455
3835 ME59:Telomere Maintenance 1_DMN-9_Cingulo_opercular -0.4275834 -2.953897 0.0031379 0 1 1 1 39 0.0973682
3849 ME59:Telomere Maintenance 2_Visual_2-16_Parieto_occipital 0.4235007 4.304642 0.0000167 0 1 2 2 39 0.0057954
3893 ME59:Telomere Maintenance 11.5_Frontoparietal_2-16_Parieto_occipital -0.4581511 -3.188361 0.0014308 0 1 1 1 39 0.0711828
3901 ME60:no enrichment 1_DMN-9_Cingulo_opercular 0.4712931 3.337070 0.0008467 0 1 1 1 39 0.0510353
3915 ME60:no enrichment 2_Visual_2-16_Parieto_occipital -0.5356343 -3.764567 0.0001668 0 1 1 2 39 0.0277485
3921 ME60:no enrichment 3_Frontoparietal_1-10_Somatomotor 0.4726565 5.825360 0.0000000 0 1 4 1 39 0.0000237
3927 ME60:no enrichment 4.5_Visual_1-8_Salience 0.5082843 3.673865 0.0002389 0 1 1 1 39 0.0343383
3928 ME60:no enrichment 4.5_Visual_1-9_Cingulo_opercular 0.1641099 3.172596 0.0015108 0 1 5 1 39 0.0722071
3957 ME60:no enrichment 10_Somatomotor-16_Parieto_occipital -0.5394229 -3.995850 0.0000645 0 1 1 1 39 0.0149434
3959 ME60:no enrichment 11.5_Frontoparietal_2-16_Parieto_occipital 0.4925328 3.534390 0.0004087 0 1 1 1 39 0.0377655
4098 ME63:response to bacterium 1_DMN-8_Salience 0.4373324 2.998471 0.0027134 0 1 1 1 39 0.0889886
4103 ME63:response to bacterium 1_DMN-16_Parieto_occipital 0.3670849 3.280077 0.0010378 0 1 2 2 39 0.0584671

Network measures vs. RNA-seq

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
20 ME10:Processing of Capped Intron-Containing Pre-mRNA efficiency_weighted 0.4615840 3.360096 0.0007792 0 1 1 2 39 0.0490868
42 ME21:negative regulation of macromolecule metabolic process efficiency_weighted 0.4640841 3.463051 0.0005341 0 1 1 2 39 0.0490868

ImmPort immune genes vs behavior

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
225 TGFb email.LIWCcdi -0.4839447 -3.734825 0.0001878 0 1 1 2 47 0.0267680
240 TGFbR prevevening.Psoriasisseverity -0.5489458 -4.248762 0.0000215 0 1 1 1 40 0.0061262

Test specific hypothesis regarding psoriasis

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
8 IL prevevening.Psoriasisseverity 0.3240673 2.333622 0.0196156 0 1 1 1 40 0.0980778
11 TCRsig prevevening.Psoriasisseverity -0.4227964 -3.109730 0.0018726 0 1 1 1 40 0.0140444
13 TGFbR prevevening.Psoriasisseverity -0.5489458 -4.248762 0.0000215 0 1 1 1 40 0.0003224

Test specific hypothesis regarding mood

[1] “no significant results”

ImmPort immune genes vs within-module connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
36 BCRsig 16:Parieto_Occipital -0.2535432 -3.614409 0.000301 0 1 2 1 39 0.054186

ImmPort immune genes vs between-module connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
52 Abx 8_Salience-9_Cingulo_opercular 0.4520895 4.842756 0.0000013 0 1 3 3 39 0.0012677
93 Agprocess 3_Frontoparietal_1-10_Somatomotor 0.4493960 4.054354 0.0000503 0 1 1 2 39 0.0248852
606 Nkcyto 2_Visual_2-3_Frontoparietal_1 0.3876656 3.606886 0.0003099 0 1 3 1 39 0.0766987
621 Nkcyto 3_Frontoparietal_1-10_Somatomotor 0.5189822 3.791640 0.0001497 0 1 1 1 39 0.0493865

ImmPort immune genes vs network measures

[1] “no significant results”

ImmPort immune genes vs food

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
64 beef Cmkn 0.2846696 5.910725 0.0e+00 0 1 3 1 39 0.0000017
68 beef IL 0.3013671 4.502722 6.7e-06 0 1 3 3 39 0.0016604

ImmPort immune genes vs metabolism

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
37 BCRsig C7:no enrichment -0.3513895 -3.614661 0.0003007 0 1 1 2 48 0.0338333
210 TNF C15:no enrichment -0.4728250 -3.717640 0.0002011 0 1 1 1 48 0.0338333

ImmPort immune genes vs metabolism (full set)

[1] “no significant results”

food vs. metabolism

note: food needs to be X variable because auto.arima doesn't handle binary Y variable

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
6 almonds C6:no enrichment 0.2202906 3.245042 0.0011743 0.000000 1.0000000 1 1 39 0.0391793
15 almonds C15:no enrichment -0.2210030 -3.272501 0.0010660 0.000000 1.0000000 2 1 39 0.0391793
50 bacon C5:TAG degradation/fatty acid transport 0.4855993 3.469639 0.0005212 0.000000 1.0000000 1 1 39 0.0214978
51 bacon C6:no enrichment -0.3965342 -2.945184 0.0032276 0.000000 1.0000000 3 2 39 0.0760797
53 bacon C8:gamma-glutamyl cycle 0.4207919 3.912190 0.0000915 0.000000 1.0000000 3 1 39 0.0090548
60 bacon C15:no enrichment 0.6163900 5.803834 0.0000000 0.000000 1.0000000 2 1 39 0.0000032
78 beets C3:no enrichment -0.4473051 -3.216464 0.0012978 0.000000 1.0000000 1 1 39 0.0401510
83 beets C8:gamma-glutamyl cycle 0.5329494 3.241925 0.0011873 -1.944102 0.0518832 3 2 39 0.0391793
85 beets C10:Glycerophospholipid Biosynthesis 0.0467584 3.723799 0.0001962 0.000000 1.0000000 3 2 39 0.0138775
86 beets C11:amino acid/neurotransmitter transporters 0.4192831 4.125347 0.0000370 0.000000 1.0000000 3 1 39 0.0061079
154 cashews C4:amino acid transport 0.4403746 3.039395 0.0023705 0.000000 1.0000000 1 1 39 0.0617587
210 eggs C15:no enrichment 0.4673767 3.503631 0.0004590 0.000000 1.0000000 2 1 39 0.0206532
265 lettuce C10:Glycerophospholipid Biosynthesis -0.2444900 -3.004286 0.0026620 0.000000 1.0000000 3 1 39 0.0658857
273 olives C3:no enrichment -0.4315704 -3.060233 0.0022116 0.000000 1.0000000 1 1 39 0.0608202
276 olives C6:no enrichment -0.2083086 -2.924024 0.0034554 0.000000 1.0000000 4 1 39 0.0766181
325 radishes C10:Glycerophospholipid Biosynthesis 0.2228328 3.611959 0.0003039 0.000000 1.0000000 3 1 39 0.0188034
326 radishes C11:amino acid/neurotransmitter transporters 0.3631870 3.815643 0.0001358 0.000000 1.0000000 2 1 39 0.0112059
343 rasberries C13:retinol biosynthesis 0.4365951 3.083902 0.0020430 0.000000 1.0000000 1 1 39 0.0594887
405 salsa C15:no enrichment 0.4902387 3.520617 0.0004305 0.000000 1.0000000 1 1 39 0.0206532
426 sausage C6:no enrichment 0.1215238 2.914724 0.0035600 0.000000 1.0000000 1 1 39 0.0766181
445 spinach C10:Glycerophospholipid Biosynthesis 0.2561149 3.566853 0.0003613 0.000000 1.0000000 3 1 39 0.0198712
446 spinach C11:amino acid/neurotransmitter transporters 0.3051983 4.469227 0.0000079 0.000000 1.0000000 2 1 39 0.0019429
462 tomatoes C12:no enrichment 0.4285563 2.826969 0.0046991 0.000000 1.0000000 1 1 39 0.0930419
475 tuna C10:Glycerophospholipid Biosynthesis 0.2955326 3.923567 0.0000872 0.000000 1.0000000 3 1 39 0.0090548
488 yogurt C8:gamma-glutamyl cycle 0.3060444 2.890878 0.0038417 0.000000 1.0000000 3 1 39 0.0792345

food vs. metabolism (individual metabolites)

note: food needs to be X variable because auto.arima doesn't handle binary Y variable

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
3 almonds valine -0.3826251 -3.159742 0.0015791 0 1 3 2 39 0.0974220
21 almonds pyrophosphate 0.2510989 4.122155 0.0000375 0 1 5 1 39 0.0109413
82 almonds creatinine -0.3265056 -3.559595 0.0003714 0 1 2 1 39 0.0393712
96 almonds acetoacetate -0.1205715 -5.017023 0.0000005 0 1 1 1 39 0.0003834
321 bacon valine 0.3538162 3.390370 0.0006980 0 1 3 1 39 0.0610386
347 bacon palmitoleic acid 0.5274874 3.883084 0.0001031 0 1 1 1 39 0.0205174
353 bacon oleic acid 0.5056522 3.660476 0.0002517 0 1 1 1 39 0.0357731
373 bacon isoleucine 0.5519404 3.584570 0.0003376 0 1 3 2 39 0.0391981
375 bacon isocitric acid 0.2824445 4.253126 0.0000211 0 1 1 2 39 0.0073740
376 bacon indole-3-lactate 0.5201959 4.057685 0.0000496 0 1 3 1 39 0.0123833
409 bacon arachidonic acid 0.4419865 3.229093 0.0012418 0 1 2 2 39 0.0868787
414 bacon acetoacetate 0.4336206 4.527680 0.0000060 0 1 1 1 39 0.0023178
415 bacon 3-hydroxybutyric acid 0.5502626 4.623944 0.0000038 0 1 2 1 39 0.0016705
416 bacon 3-hydroxybutanoic acid 0.6083959 4.796807 0.0000016 0 1 3 2 39 0.0009399
422 bacon 2-deoxytetronic acid 0.4792836 3.938299 0.0000821 0 1 2 1 39 0.0179407
490 beef hexitol -0.5537625 -4.081664 0.0000447 0 1 1 1 39 0.0120316
533 beets valine 0.4970490 4.620920 0.0000038 0 1 4 2 39 0.0016705
535 beets uric acid 0.1948756 3.289914 0.0010022 0 1 3 2 39 0.0796734
558 beets parabanic acid -0.5039417 -3.723408 0.0001966 0 1 1 1 39 0.0298930
563 beets oxalic acid -0.5019729 -3.610104 0.0003061 0 1 1 1 39 0.0389433
603 beets glutamine 0.2574723 3.239227 0.0011985 0 1 1 2 39 0.0868787
622 beets arachidic acid 0.2349704 3.421099 0.0006237 0 1 2 1 39 0.0574864
759 blueberries succinic acid 0.5102324 3.656514 0.0002557 0 1 1 1 39 0.0357731
978 carrots phosphate -0.2465809 -3.194036 0.0014030 0 1 5 2 39 0.0908822
997 carrots methionine sulfoxide -0.4014004 -3.965725 0.0000732 0 1 1 2 39 0.0170640
1017 carrots hippuric acid 0.3989848 3.242713 0.0011840 0 1 2 1 39 0.0868787
1122 cashews histidine 0.4617943 3.206779 0.0013423 0 1 1 1 39 0.0902955
1133 cashews glutamine 0.5530772 5.287091 0.0000001 0 1 2 2 39 0.0002174
1134 cashews glutamic acid 0.1533731 3.486390 0.0004896 0 1 2 1 39 0.0489308
1170 cheese uridine 0.4535425 3.174513 0.0015009 0 1 1 1 39 0.0954562
1182 cheese sucrose -0.5553840 -4.154594 0.0000326 0 1 1 1 39 0.0103625
1394 eggs sucrose -0.4443983 -5.691307 0.0000000 0 1 5 1 39 0.0000441
1415 eggs N-methylalanine 0.4275745 5.070794 0.0000004 0 1 3 1 39 0.0003834
1476 eggs 3-hydroxybutanoic acid 0.5331454 3.728757 0.0001924 0 1 3 2 39 0.0298930
1482 eggs 2-deoxytetronic acid 0.4270041 3.787919 0.0001519 0 1 2 1 39 0.0265698
1636 kale mannose 0.2494495 5.008706 0.0000005 0 1 3 1 39 0.0003834
1641 kale leucine 0.3249949 3.265822 0.0010915 0 1 2 2 39 0.0848434
1846 lettuce methionine -0.3959437 -3.420747 0.0006245 0 1 1 2 39 0.0574864
1906 lettuce 2-deoxytetronic acid -0.4961257 -3.201002 0.0013695 0 1 2 1 39 0.0903875
1966 olives indole-3-lactate 0.1876956 3.838238 0.0001239 0 1 3 1 39 0.0228144
2028 onions threitol 0.4967683 3.570429 0.0003564 0 1 1 1 39 0.0391981
2100 onions butane-2,3-diol -0.4587485 -3.218933 0.0012867 0 1 1 1 39 0.0882516
2270 radishes methionine 0.4535638 3.877401 0.0001056 0 1 1 2 39 0.0205174
2301 radishes glucose -0.3326252 -3.429479 0.0006047 0 1 2 1 39 0.0574864
2421 rasberries behenic acid 0.4629631 3.299668 0.0009680 0 1 1 1 39 0.0787450
2447 red_peppers trans-4-hydroxyproline 0.4706598 3.514981 0.0004398 0 1 1 2 39 0.0452461
2526 red_peppers benzoic acid -0.4028289 -3.158195 0.0015875 0 1 2 1 39 0.0974220
2542 red_peppers 2-deoxytetronic acid -0.4797882 -3.377255 0.0007321 0 1 1 1 39 0.0624632
2831 salsa glucose -0.2251394 -3.241221 0.0011902 0 1 3 2 39 0.0868787
2942 sauerkraut dehydroabietic acid 0.3775165 3.643073 0.0002694 0 1 1 2 39 0.0362449
3105 spinach p-cresol -0.3352019 -3.568824 0.0003586 0 1 1 2 39 0.0391981
3118 spinach methionine 0.3842821 3.368809 0.0007549 0 1 1 2 39 0.0628756
3181 tomatoes xylulose 0.4656653 3.234768 0.0012174 0 1 1 1 39 0.0868787
3330 tuna methionine 0.4999807 3.605357 0.0003117 0 1 1 1 39 0.0389433
3387 tuna 2-ketoisocaproic acid 0.4973010 3.579662 0.0003440 0 1 1 1 39 0.0391981
3409 yogurt succinic acid 0.4793869 3.400780 0.0006719 0 1 1 1 39 0.0602677
3429 yogurt N-methylalanine 0.6145740 3.728804 0.0001924 0 1 1 2 39 0.0298930

behav vs. metabolsm

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
83 afterscan.pulse C8:gamma-glutamyl cycle -0.2449325 -3.282730 0.0010281 -2.616619 0.0088805 3 2 42 0.0586001
98 afterscan.systolic C8:gamma-glutamyl cycle -0.0884191 -3.864130 0.0001115 -2.583350 0.0097846 1 2 47 0.0105912
105 afterscan.systolic C15:no enrichment -0.3441672 -3.190939 0.0014181 0.000000 1.0000000 1 2 47 0.0673603
145 prevevening.Alcohol C10:Glycerophospholipid Biosynthesis 0.5573542 4.361358 0.0000129 0.000000 1.0000000 1 2 40 0.0036838
275 zeo.zq C5:TAG degradation/fatty acid transport -0.5929204 -4.032916 0.0000551 0.000000 1.0000000 1 1 30 0.0078502
279 zeo.zq C9:fatty acid transport -0.5228525 -3.353892 0.0007968 0.000000 1.0000000 1 1 30 0.0567745

behav vs. metabolsm (full set)

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
26 panas.positive phenylalanine -0.4345666 -3.356868 0.0007883 0 1 1 2 45 0.0610635
127 panas.negative pyrophosphate 0.4489783 3.280615 0.0010358 0 1 1 2 45 0.0695374
222 panas.fatigue tocopherol gamma- 0.2456932 3.979372 0.0000691 0 1 5 3 45 0.0121983
478 afterscan.diastolic isothreonic acid 0.4623737 3.490161 0.0004827 0 1 2 1 47 0.0462961
533 afterscan.pulse valine -0.2883961 -3.253783 0.0011388 0 1 4 1 42 0.0739848
608 afterscan.pulse ethanolamine -0.3763563 -3.204757 0.0013518 0 1 1 2 42 0.0824985
639 afterscan.systolic valine -0.2054067 -3.281182 0.0010337 0 1 3 2 47 0.0695374
665 afterscan.systolic palmitoleic acid -0.2750445 -3.574508 0.0003509 0 1 3 3 47 0.0353344
691 afterscan.systolic isoleucine -0.2974056 -4.796971 0.0000016 0 1 1 2 47 0.0010277
694 afterscan.systolic indole-3-lactate -0.1879323 -3.281084 0.0010341 0 1 1 2 47 0.0695374
733 afterscan.systolic 3-hydroxybutyric acid -0.3451860 -3.135932 0.0017131 0 1 1 2 47 0.0985761
734 afterscan.systolic 3-hydroxybutanoic acid -0.3690931 -3.803333 0.0001428 0 1 1 2 47 0.0179702
740 afterscan.systolic 2-deoxytetronic acid -0.3651745 -4.246195 0.0000217 0 1 1 2 47 0.0054738
903 morning.Soreness isoleucine -0.0680469 3.412309 0.0006442 0 1 1 1 47 0.0540549
1033 prevevening.Alcohol erythritol 0.5477280 4.539147 0.0000056 0 1 1 2 40 0.0018959
1040 prevevening.Alcohol butane-2,3-diol 0.7919126 7.378376 0.0000000 0 1 1 2 40 0.0000000
1058 prevevening.Alcohol 2-deoxytetronic acid 0.5178265 3.755972 0.0001727 0 1 1 1 40 0.0193198
1059 prevevening.Alcohol 2-deoxyerythritol 0.6151586 4.703985 0.0000026 0 1 1 1 40 0.0010277
1079 prevevening.Guthealth shikimic acid -0.2081308 -3.591000 0.0003294 0 1 3 1 40 0.0349176
1170 prevevening.Psoriasisseverity uridine -0.4506205 -3.207389 0.0013395 0 1 1 1 40 0.0824985
1237 prevevening.Psoriasisseverity glycerol -0.5456344 -3.986484 0.0000671 0 1 1 1 40 0.0121983
1244 prevevening.Psoriasisseverity ethanolamine -0.4270401 -3.447870 0.0005650 0 1 2 1 40 0.0494766
1508 temp.mean phosphate 0.5047107 3.860573 0.0001131 0 1 3 2 48 0.0166652
1515 temp.mean p-cresol 0.2648638 3.811706 0.0001380 0 1 3 1 48 0.0179702
1714 email.LIWCnegemo stearic acid 0.4493136 4.361381 0.0000129 0 1 3 2 47 0.0037185
1726 email.LIWCnegemo palmitic acid 0.4398247 3.343296 0.0008279 0 1 1 2 47 0.0617549
1736 email.LIWCnegemo N-acetylglycine -0.4503959 -3.459547 0.0005411 0 1 1 1 47 0.0494766
1898 email.LIWCposemo acetoacetate -0.1480226 -3.174649 0.0015002 0 1 2 1 47 0.0888636
1937 zeo.zq palmitoleic acid -0.5745431 -4.741003 0.0000021 0 1 1 2 30 0.0010277
1938 zeo.zq palmitic acid -0.5421246 -3.854755 0.0001158 0 1 3 1 30 0.0166652
1943 zeo.zq oleic acid -0.6041199 -5.085505 0.0000004 0 1 2 1 30 0.0003692
1949 zeo.zq myristic acid -0.4806070 -3.393453 0.0006902 0 1 2 1 30 0.0556003
1958 zeo.zq linoleic acid -0.5866144 -3.967335 0.0000727 0 1 1 1 30 0.0121983
1966 zeo.zq indole-3-lactate -0.5482238 -3.761454 0.0001689 0 1 3 1 30 0.0193198
1975 zeo.zq heptadecanoic acid -0.5046617 -4.020279 0.0000581 0 1 3 1 30 0.0121983

metabolism vs. within-network connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
4 C1:no enrichment 4.5:Visual_1 -0.2919575 -3.321244 0.0008962 0 1 1 2 39 0.0403277
38 C4:amino acid transport 2:Visual_2 0.4713183 4.142404 0.0000344 0 1 1 2 39 0.0061863
51 C5:TAG degradation/fatty acid transport 3:Fronto_Parietal -0.4907486 -3.513195 0.0004428 0 1 1 1 39 0.0265651
99 C9:fatty acid transport 3:Fronto_Parietal -0.5119455 -3.720959 0.0001985 0 1 1 1 39 0.0178621

metabolism vs. within-network connectivity (full set of metabolites)

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
46 uridine 11.5:Fronto_Parietal_2 -0.4632558 -3.132341 0.0017342 0.000000 1.0000000 1 1 39 0.0880525
111 tocopherol gamma- 3:Fronto_Parietal -0.5118872 -3.714890 0.0002033 0.000000 1.0000000 1 1 39 0.0287320
142 threonine 11.5:Fronto_Parietal_2 -0.3492588 -4.117677 0.0000383 0.000000 1.0000000 1 1 39 0.0115171
158 threitol 2:Visual_2 -0.3000209 -4.036374 0.0000543 2.985168 0.0028342 4 2 39 0.0115171
220 shikimic acid 4.5:Visual_1 -0.2645246 -3.056214 0.0022415 0.000000 1.0000000 1 2 39 0.0950401
252 pyrophosphate 16:Parieto_Occipital -0.3386550 -3.114178 0.0018446 0.000000 1.0000000 2 1 39 0.0880525
278 phosphate 2:Visual_2 0.4524926 3.236442 0.0012103 0.000000 1.0000000 1 1 39 0.0733094
351 palmitic acid 3:Fronto_Parietal -0.4739132 -3.360313 0.0007785 0.000000 1.0000000 1 1 39 0.0582534
398 ornithine 2:Visual_2 0.5281968 3.902194 0.0000953 0.000000 1.0000000 1 2 39 0.0173219
411 oleic acid 3:Fronto_Parietal -0.4849086 -3.462432 0.0005353 0.000000 1.0000000 1 1 39 0.0523786
468 N-acetylmannosamine 16:Parieto_Occipital -0.4598156 -4.036191 0.0000543 0.000000 1.0000000 2 1 39 0.0115171
483 myristic acid 3:Fronto_Parietal -0.4378219 -3.041119 0.0023570 0.000000 1.0000000 1 1 39 0.0967133
578 lysine 2:Visual_2 0.3617311 3.287497 0.0010108 0.000000 1.0000000 1 2 39 0.0676719
591 linoleic acid 3:Fronto_Parietal -0.4792145 -3.406805 0.0006573 0.000000 1.0000000 1 1 39 0.0557374
636 lactic acid 16:Parieto_Occipital 0.3652643 3.721859 0.0001978 0.000000 1.0000000 2 1 39 0.0287320
700 indole-3-acetate 4.5:Visual_1 -0.4284300 -3.664490 0.0002478 0.000000 1.0000000 1 2 39 0.0315242
762 hexuronic acid 7:Ventral_Attention -0.5134593 -4.066088 0.0000478 0.000000 1.0000000 1 2 39 0.0115171
795 heptadecanoic acid 3:Fronto_Parietal -0.4461242 -3.110290 0.0018690 0.000000 1.0000000 1 1 39 0.0880525
807 glycolic acid 3:Fronto_Parietal 0.3229797 3.065420 0.0021736 0.000000 1.0000000 1 2 39 0.0950401
811 glycolic acid 8:Salience -0.2800134 -3.086241 0.0020270 0.000000 1.0000000 2 1 39 0.0920857
854 glyceric acid 2:Visual_2 -0.5402443 -3.248995 0.0011581 0.000000 1.0000000 3 2 39 0.0733094
861 glyceric acid 10:Somatomotor -0.5560143 -3.517239 0.0004361 0.000000 1.0000000 1 2 39 0.0468721
938 erythritol 2:Visual_2 -0.5262830 -3.172174 0.0015130 1.829355 0.0673464 3 2 39 0.0836769
963 cystine 3:Fronto_Parietal 0.4989520 3.513533 0.0004422 0.000000 1.0000000 1 1 39 0.0468721
969 cystine 10:Somatomotor 0.4501336 3.148038 0.0016437 0.000000 1.0000000 1 1 39 0.0871162
1000 cholesterol 4.5:Visual_1 -0.3443407 -3.288479 0.0010073 0.000000 1.0000000 1 2 39 0.0676719
1008 cholesterol 16:Parieto_Occipital -0.3961729 -3.387183 0.0007061 0.000000 1.0000000 1 2 39 0.0561383
1035 beta-alanine 3:Fronto_Parietal -0.6053265 -4.741568 0.0000021 0.000000 1.0000000 1 1 39 0.0026975
1083 arachidonic acid 3:Fronto_Parietal -0.4549437 -3.173647 0.0015054 0.000000 1.0000000 1 1 39 0.0836769
1132 alanine 4.5:Visual_1 0.3570569 3.413885 0.0006404 0.000000 1.0000000 1 2 39 0.0557374
1140 alanine 16:Parieto_Occipital 0.1581938 4.127173 0.0000367 0.000000 1.0000000 2 2 39 0.0115171

metabolism vs. between-network connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
67 C2:Glycerophospholipid Biosynthesis 1_DMN-2_Visual_2 0.3699088 3.789578 0.0001509 0 1 1 2 39 0.0497981
479 C8:gamma-glutamyl cycle 2_Visual_2-9_Cingulo_opercular -0.4982153 -3.588415 0.0003327 0 1 1 1 39 0.0823419
806 C13:retinol biosynthesis 2_Visual_2-5_Dorsal_Attention 0.5049880 4.840403 0.0000013 0 1 1 2 39 0.0012828
812 C13:retinol biosynthesis 2_Visual_2-15_Medial_Parietal -0.3254479 -3.823477 0.0001316 0 1 2 1 39 0.0497981

metabolism vs. within-network connectivity (full set of metabolites)

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
477 tryptophan 2_Visual_2-7_Ventral_Attention 0.2778440 4.231954 0.0000232 0.000000 1.0000000 1 1 39 0.0146621
1173 stearic acid 7_Ventral_Attention-16_Parieto_occipital -0.3359196 -4.660583 0.0000032 0.000000 1.0000000 1 2 39 0.0044119
1368 pyrophosphate 7_Ventral_Attention-10_Somatomotor 0.0904838 3.521920 0.0004284 0.000000 1.0000000 1 1 39 0.0843101
1536 phosphate 2_Visual_2-10_Somatomotor 0.5182126 3.783949 0.0001544 0.000000 1.0000000 1 1 39 0.0490863
1813 parabanic acid 4.5_Visual_1-5_Dorsal_Attention 0.5197498 3.810100 0.0001389 0.000000 1.0000000 2 2 39 0.0462771
1998 p-cresol 2_Visual_2-10_Somatomotor 0.4963127 3.681908 0.0002315 2.086285 0.0369528 1 2 39 0.0589269
2103 oxoproline 9_Cingulo_opercular-10_Somatomotor -0.4861749 -3.474411 0.0005120 0.000000 1.0000000 1 1 39 0.0895447
2391 N-methylalanine 2_Visual_2-7_Ventral_Attention 0.1951298 4.217235 0.0000247 0.000000 1.0000000 1 1 39 0.0146621
2424 N-methylalanine 7_Ventral_Attention-10_Somatomotor 0.2830657 4.350147 0.0000136 0.000000 1.0000000 1 1 39 0.0105753
2502 N-acetylornithine 9_Cingulo_opercular-16_Parieto_occipital -0.3874488 -3.661545 0.0002507 0.000000 1.0000000 2 2 39 0.0604790
2612 N-acetylglycine 4.5_Visual_1-16_Parieto_occipital 0.4570714 3.763445 0.0001676 0.000000 1.0000000 1 2 39 0.0509762
3070 malic acid 4.5_Visual_1-9_Cingulo_opercular -0.0608014 -3.964164 0.0000737 0.000000 1.0000000 3 3 39 0.0343520
3378 lauric acid 2_Visual_2-3_Frontoparietal_1 0.3505957 3.677163 0.0002358 0.000000 1.0000000 5 2 39 0.0589269
3546 isothreonic acid 7_Ventral_Attention-10_Somatomotor 0.2434747 3.702459 0.0002135 0.000000 1.0000000 3 2 39 0.0589269
3554 isothreonic acid 8_Salience-16_Parieto_occipital -0.4940536 -3.548706 0.0003871 0.000000 1.0000000 1 1 39 0.0843101
3564 isothreonic acid 15_Medial_Parietal-16_Parieto_occipital -0.4921482 -3.530635 0.0004146 0.000000 1.0000000 1 1 39 0.0843101
3581 isoleucine 2_Visual_2-9_Cingulo_opercular -0.5257514 -3.859819 0.0001135 0.000000 1.0000000 1 1 39 0.0441024
3965 hydroxycarbamate 1_DMN-7_Ventral_Attention -0.4806002 -4.145885 0.0000339 0.000000 1.0000000 1 2 39 0.0182167
4128 hippuric acid 4.5_Visual_1-11.5_Frontoparietal_2 -0.2898329 -4.394465 0.0000111 0.000000 1.0000000 4 1 39 0.0097109
4229 hexonic acid 1_DMN-7_Ventral_Attention -0.2540013 -3.681311 0.0002320 0.000000 1.0000000 1 2 39 0.0589269
4373 heptadecanoic acid 2_Visual_2-9_Cingulo_opercular 0.0765466 3.507649 0.0004521 0.000000 1.0000000 4 1 39 0.0843101
4476 glycolic acid 8_Salience-11.5_Frontoparietal_2 -0.5594999 -4.213454 0.0000251 0.000000 1.0000000 1 1 39 0.0146621
4477 glycolic acid 8_Salience-15_Medial_Parietal -0.3525371 -3.516893 0.0004366 0.000000 1.0000000 2 1 39 0.0843101
4656 glycerol 4.5_Visual_1-11.5_Frontoparietal_2 -0.4737301 -3.928124 0.0000856 0.000000 1.0000000 1 3 39 0.0374335
4704 glyceric acid 2_Visual_2-10_Somatomotor -0.6392506 -5.191310 0.0000002 0.000000 1.0000000 1 1 39 0.0005562
4821 glutamic acid 1_DMN-4.5_Visual_1 0.5739472 4.944727 0.0000008 0.000000 1.0000000 1 1 39 0.0013336
5145 ethanolamine 10_Somatomotor-16_Parieto_occipital 0.5372334 3.973528 0.0000708 0.000000 1.0000000 1 1 39 0.0343520
5320 cystine 5_Dorsal_Attention-8_Salience 0.2748730 3.598844 0.0003196 0.000000 1.0000000 1 2 39 0.0745387
5556 capric acid 2_Visual_2-3_Frontoparietal_1 0.5098285 3.873804 0.0001071 0.000000 1.0000000 3 2 39 0.0440953
5688 beta-alanine 2_Visual_2-3_Frontoparietal_1 0.5272425 5.166492 0.0000002 -1.971887 0.0486225 5 1 39 0.0005562
5700 beta-alanine 3_Frontoparietal_1-7_Ventral_Attention 0.4853236 4.507050 0.0000066 0.000000 1.0000000 2 1 39 0.0076647
5822 behenic acid 2_Visual_2-5_Dorsal_Attention 0.4741387 4.442449 0.0000089 0.000000 1.0000000 1 2 39 0.0088890
5828 behenic acid 2_Visual_2-15_Medial_Parietal -0.3325290 -3.832363 0.0001269 0.000000 1.0000000 2 1 39 0.0443960
5851 behenic acid 5_Dorsal_Attention-11.5_Frontoparietal_2 -0.5296709 -3.833228 0.0001265 0.000000 1.0000000 1 1 39 0.0443960
5905 asparagine 4.5_Visual_1-5_Dorsal_Attention -0.4893505 -3.504221 0.0004579 0.000000 1.0000000 1 1 39 0.0843101
6020 arachidic acid 2_Visual_2-5_Dorsal_Attention 0.5059696 3.575622 0.0003494 0.000000 1.0000000 1 1 39 0.0788507
6026 arachidic acid 2_Visual_2-15_Medial_Parietal -0.2992257 -3.510526 0.0004472 0.000000 1.0000000 2 1 39 0.0843101
6080 aminomalonate 1_DMN-10_Somatomotor 0.4958656 5.271652 0.0000001 0.000000 1.0000000 1 2 39 0.0005562
6696 2-hydroxyvaleric acid 3_Frontoparietal_1-16_Parieto_occipital 0.5235070 3.700396 0.0002153 0.000000 1.0000000 1 1 39 0.0589269
6815 2-deoxytetronic acid 2_Visual_2-9_Cingulo_opercular -0.4955121 -3.440666 0.0005803 0.000000 1.0000000 5 1 39 0.0990162
6869 2-deoxyerythritol 1_DMN-7_Ventral_Attention -0.4925173 -3.486961 0.0004885 0.000000 1.0000000 1 1 39 0.0876369

metabolism vs. metabolism

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
4 C1:no enrichment C5:TAG degradation/fatty acid transport 0.6890816 6.587822 0.0000000 0 1 1 1 48 0.0000000
5 C1:no enrichment C6:no enrichment -0.4045261 -2.405141 0.0161662 0 1 1 3 48 0.0487123
7 C1:no enrichment C8:gamma-glutamyl cycle 0.5451481 4.154940 0.0000325 0 1 3 2 48 0.0003596
8 C1:no enrichment C9:fatty acid transport 0.5248739 5.359169 0.0000001 0 1 1 2 48 0.0000025
9 C1:no enrichment C10:Glycerophospholipid Biosynthesis 0.4659905 3.648858 0.0002634 0 1 1 1 48 0.0025144
11 C1:no enrichment C12:no enrichment 0.4397191 3.391981 0.0006939 0 1 1 1 48 0.0050247
16 C2:Glycerophospholipid Biosynthesis C3:no enrichment 0.3976456 3.002559 0.0026772 0 1 1 1 48 0.0133860
19 C2:Glycerophospholipid Biosynthesis C6:no enrichment -0.2467659 -2.580406 0.0098684 0 1 3 2 48 0.0345395
20 C2:Glycerophospholipid Biosynthesis C7:no enrichment 0.5162027 4.175705 0.0000297 0 1 1 1 48 0.0003466
22 C2:Glycerophospholipid Biosynthesis C9:fatty acid transport -0.5048899 -5.746826 0.0000000 0 1 4 1 48 0.0000003
23 C2:Glycerophospholipid Biosynthesis C10:Glycerophospholipid Biosynthesis 0.3277576 2.533799 0.0112833 0 1 2 2 48 0.0382178
26 C2:Glycerophospholipid Biosynthesis C13:retinol biosynthesis -0.4028141 -3.049087 0.0022954 0 1 1 1 48 0.0123032
27 C2:Glycerophospholipid Biosynthesis C14:no enrichment 0.2320222 2.807379 0.0049946 0 1 1 2 48 0.0220350
30 C3:no enrichment C2:Glycerophospholipid Biosynthesis 0.3976456 3.002559 0.0026772 0 1 1 1 48 0.0133860
37 C3:no enrichment C10:Glycerophospholipid Biosynthesis 0.3747322 2.200378 0.0277801 0 1 2 1 48 0.0799153
38 C3:no enrichment C11:amino acid/neurotransmitter transporters -0.8202003 -9.933112 0.0000000 0 1 1 1 48 0.0000000
39 C3:no enrichment C12:no enrichment 0.4405499 3.399932 0.0006740 0 1 1 1 48 0.0050247
46 C4:amino acid transport C5:TAG degradation/fatty acid transport -0.3294257 -2.417252 0.0156382 0 1 1 1 48 0.0482944
52 C4:amino acid transport C11:amino acid/neurotransmitter transporters 0.5583649 4.663066 0.0000031 0 1 1 1 48 0.0000545
57 C5:TAG degradation/fatty acid transport C1:no enrichment 0.6890816 6.587822 0.0000000 0 1 1 1 48 0.0000000
60 C5:TAG degradation/fatty acid transport C4:amino acid transport -0.3294257 -2.417252 0.0156382 0 1 1 1 48 0.0482944
63 C5:TAG degradation/fatty acid transport C8:gamma-glutamyl cycle 0.4516018 2.644881 0.0081720 0 1 3 2 48 0.0305300
64 C5:TAG degradation/fatty acid transport C9:fatty acid transport 0.6064650 5.284430 0.0000001 0 1 1 1 48 0.0000029
65 C5:TAG degradation/fatty acid transport C10:Glycerophospholipid Biosynthesis 0.4216788 3.221932 0.0012733 0 1 1 1 48 0.0084966
67 C5:TAG degradation/fatty acid transport C12:no enrichment 0.3931727 2.962568 0.0030508 0 1 1 1 48 0.0148995
70 C5:TAG degradation/fatty acid transport C15:no enrichment 0.4199049 3.205469 0.0013484 0 1 1 1 48 0.0084966
71 C6:no enrichment C1:no enrichment -0.4045261 -3.064574 0.0021798 0 1 1 1 48 0.0123032
75 C6:no enrichment C5:TAG degradation/fatty acid transport -0.3618451 -2.689154 0.0071633 0 1 1 1 48 0.0273509
76 C6:no enrichment C7:no enrichment -0.4114171 -3.127308 0.0017641 0 1 1 1 48 0.0105849
77 C6:no enrichment C8:gamma-glutamyl cycle -0.7419241 -4.875496 0.0000011 0 1 1 2 48 0.0000228
79 C6:no enrichment C10:Glycerophospholipid Biosynthesis -0.3815505 -2.732399 0.0062875 0 1 2 1 48 0.0258897
83 C6:no enrichment C14:no enrichment 0.0524431 -2.123114 0.0337443 0 1 1 2 48 0.0942611
84 C6:no enrichment C15:no enrichment -0.3299558 -2.421617 0.0154516 0 1 1 1 48 0.0482944
86 C7:no enrichment C2:Glycerophospholipid Biosynthesis 0.5162027 4.175705 0.0000297 0 1 1 1 48 0.0003466
90 C7:no enrichment C6:no enrichment -0.4114171 -2.764176 0.0057067 0 1 3 2 48 0.0239680
92 C7:no enrichment C9:fatty acid transport -0.3626047 -4.558542 0.0000052 0 1 3 2 48 0.0000832
93 C7:no enrichment C10:Glycerophospholipid Biosynthesis 0.4440426 2.701100 0.0069111 0 1 2 1 48 0.0273197
95 C7:no enrichment C12:no enrichment -0.2917767 -2.113449 0.0345624 0 1 1 1 48 0.0942611
97 C7:no enrichment C14:no enrichment 0.2119636 2.839019 0.0045252 0 1 1 2 48 0.0215978
99 C8:gamma-glutamyl cycle C1:no enrichment 0.5451481 4.505202 0.0000066 0 1 1 1 48 0.0000995
103 C8:gamma-glutamyl cycle C5:TAG degradation/fatty acid transport 0.4516018 3.506741 0.0004536 0 1 1 1 48 0.0038105
104 C8:gamma-glutamyl cycle C6:no enrichment -0.7419241 -7.666389 0.0000000 0 1 1 1 48 0.0000000
107 C8:gamma-glutamyl cycle C10:Glycerophospholipid Biosynthesis 0.4517353 2.704149 0.0068480 0 1 2 1 48 0.0273197
112 C8:gamma-glutamyl cycle C15:no enrichment 0.4064254 3.081802 0.0020575 0 1 1 1 48 0.0120022
113 C9:fatty acid transport C1:no enrichment 0.5248739 4.272218 0.0000194 0 1 1 1 48 0.0002540
114 C9:fatty acid transport C2:Glycerophospholipid Biosynthesis -0.5048899 -4.052410 0.0000507 0 1 1 1 48 0.0005323
117 C9:fatty acid transport C5:TAG degradation/fatty acid transport 0.6064650 5.284430 0.0000001 0 1 1 1 48 0.0000029
119 C9:fatty acid transport C7:no enrichment -0.3626047 -2.695653 0.0070251 0 1 1 1 48 0.0273197
123 C9:fatty acid transport C12:no enrichment 0.4504738 3.495749 0.0004727 0 1 1 1 48 0.0038182
124 C9:fatty acid transport C13:retinol biosynthesis 0.3751299 2.803721 0.0050517 0 1 1 1 48 0.0220350
127 C10:Glycerophospholipid Biosynthesis C1:no enrichment 0.4659905 3.648858 0.0002634 0 1 1 1 48 0.0025144
128 C10:Glycerophospholipid Biosynthesis C2:Glycerophospholipid Biosynthesis 0.3277576 2.403534 0.0162374 0 1 1 1 48 0.0487123
129 C10:Glycerophospholipid Biosynthesis C3:no enrichment 0.3747322 2.800263 0.0051061 0 1 1 1 48 0.0220350
130 C10:Glycerophospholipid Biosynthesis C4:amino acid transport -0.3014963 -2.190766 0.0284687 0 1 1 1 48 0.0807896
131 C10:Glycerophospholipid Biosynthesis C5:TAG degradation/fatty acid transport 0.4216788 3.221932 0.0012733 0 1 1 1 48 0.0084966
133 C10:Glycerophospholipid Biosynthesis C7:no enrichment 0.4440426 4.287575 0.0000181 0 1 1 2 48 0.0002529
134 C10:Glycerophospholipid Biosynthesis C8:gamma-glutamyl cycle 0.4517353 2.315923 0.0205625 0 1 1 2 48 0.0608186
136 C10:Glycerophospholipid Biosynthesis C11:amino acid/neurotransmitter transporters -0.3119901 -2.275088 0.0229007 0 1 1 1 48 0.0667936
137 C10:Glycerophospholipid Biosynthesis C12:no enrichment 0.2919104 3.199715 0.0013756 0 1 2 1 48 0.0084966
143 C11:amino acid/neurotransmitter transporters C3:no enrichment -0.8202003 -9.933112 0.0000000 0 1 1 1 48 0.0000000
144 C11:amino acid/neurotransmitter transporters C4:amino acid transport 0.5583649 4.663066 0.0000031 0 1 1 1 48 0.0000545
155 C12:no enrichment C1:no enrichment 0.4397191 3.515155 0.0004395 0 1 1 2 48 0.0038105
157 C12:no enrichment C3:no enrichment 0.4405499 3.399932 0.0006740 0 1 1 1 48 0.0050247
159 C12:no enrichment C5:TAG degradation/fatty acid transport 0.3931727 3.042854 0.0023435 0 1 1 2 48 0.0123032
160 C12:no enrichment C6:no enrichment 0.2742817 2.634104 0.0084360 0 1 1 2 48 0.0305440
161 C12:no enrichment C7:no enrichment -0.2917767 -2.113449 0.0345624 0 1 1 1 48 0.0942611
163 C12:no enrichment C9:fatty acid transport 0.4504738 3.571626 0.0003548 0 1 1 2 48 0.0032392
167 C12:no enrichment C14:no enrichment -0.1437338 -2.429010 0.0151401 0 1 1 2 48 0.0482944
170 C13:retinol biosynthesis C2:Glycerophospholipid Biosynthesis -0.4028141 -3.049087 0.0022954 0 1 1 1 48 0.0123032
174 C13:retinol biosynthesis C6:no enrichment 0.1778837 2.475978 0.0132872 0 1 3 2 48 0.0442906
177 C13:retinol biosynthesis C9:fatty acid transport 0.3751299 2.798033 0.0051415 0 1 1 2 48 0.0220350
181 C13:retinol biosynthesis C14:no enrichment -0.2225233 -2.443461 0.0145471 0 1 1 2 48 0.0477328
182 C13:retinol biosynthesis C15:no enrichment -0.3437873 -2.640159 0.0082867 0 1 1 2 48 0.0305300
201 C15:no enrichment C5:TAG degradation/fatty acid transport 0.4199049 3.205469 0.0013484 0 1 1 1 48 0.0084966
204 C15:no enrichment C8:gamma-glutamyl cycle 0.4064254 2.828234 0.0046806 0 1 1 2 48 0.0218426
209 C15:no enrichment C13:retinol biosynthesis -0.3437873 -2.536425 0.0111991 0 1 1 1 48 0.0382178
210 C15:no enrichment C14:no enrichment 0.0366473 2.603223 0.0092352 0 1 1 2 48 0.0328710

within-network connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
4 1:Default 5:Dorsal_Attention 0.3185463 4.597053 0.0000043 -0.0551561 0.9560141 1 1 84 0.0001131
13 2:Visual_2 3:Fronto_Parietal 0.3897698 3.876967 0.0001058 0.0000000 1.0000000 2 1 84 0.0019945
19 2:Visual_2 10:Somatomotor 0.5531002 5.984241 0.0000000 0.0000000 1.0000000 2 1 84 0.0000003
20 2:Visual_2 11.5:Fronto_Parietal_2 0.2254638 2.594460 0.0094740 0.0000000 1.0000000 2 1 84 0.0568437
24 3:Fronto_Parietal 2:Visual_2 0.3897698 3.065847 0.0021705 0.0362498 0.9710832 1 1 84 0.0204651
29 3:Fronto_Parietal 9:Cingulo_opercular 0.2837626 3.286323 0.0010150 0.0000000 1.0000000 2 1 84 0.0133986
35 4.5:Visual_1 2:Visual_2 0.1980089 2.711301 0.0067020 0.0133181 0.9893740 1 1 84 0.0483741
40 4.5:Visual_1 9:Cingulo_opercular -0.3220231 -3.093804 0.0019761 0.0000000 1.0000000 2 1 84 0.0200648
41 4.5:Visual_1 10:Somatomotor 0.4784037 5.224627 0.0000002 0.0000000 1.0000000 2 1 84 0.0000115
45 5:Dorsal_Attention 1:Default 0.3185463 4.597063 0.0000043 -0.0348452 0.9722031 1 1 84 0.0001131
49 5:Dorsal_Attention 7:Ventral_Attention -0.2303057 -3.552566 0.0003815 -0.0614743 0.9509814 1 1 84 0.0055952
52 5:Dorsal_Attention 10:Somatomotor -0.3845739 -2.665129 0.0076959 0.0662959 0.9471422 1 1 84 0.0483741
59 7:Ventral_Attention 4.5:Visual_1 0.3610736 3.606887 0.0003099 0.0000000 1.0000000 2 1 84 0.0051132
72 8:Salience 7:Ventral_Attention 0.0528322 2.561591 0.0104194 -0.0004367 0.9996516 1 1 84 0.0597982
76 8:Salience 15:Medial_Parietal 0.2793899 2.666848 0.0076566 0.0000000 1.0000000 1 1 84 0.0483741
79 9:Cingulo_opercular 2:Visual_2 0.1686618 2.784183 0.0053663 0.0478780 0.9618135 1 1 84 0.0442718
80 9:Cingulo_opercular 3:Fronto_Parietal 0.2837626 2.788218 0.0052999 0.0000000 1.0000000 2 1 84 0.0442718
81 9:Cingulo_opercular 4.5:Visual_1 -0.3220231 -3.121163 0.0018014 0.0000000 1.0000000 2 1 84 0.0198152
90 10:Somatomotor 2:Visual_2 0.5531002 4.460354 0.0000082 -0.0250494 0.9800156 1 1 84 0.0001800
92 10:Somatomotor 4.5:Visual_1 0.4784037 4.876476 0.0000011 0.0000000 1.0000000 2 1 84 0.0000475
93 10:Somatomotor 5:Dorsal_Attention -0.3845739 -2.665130 0.0076959 -0.0575587 0.9541001 1 1 84 0.0483741
101 11.5:Fronto_Parietal_2 2:Visual_2 0.2254638 3.247285 0.0011651 0.0439250 0.9649642 1 1 84 0.0139814
108 11.5:Fronto_Parietal_2 10:Somatomotor 0.1113560 2.435943 0.0148530 0.1097110 0.9126386 1 1 84 0.0816916
117 15:Medial_Parietal 8:Salience 0.2793899 2.725729 0.0064160 0.0000000 1.0000000 2 1 84 0.0483741

between-network connectivity

[1] “skipping printout”

within-network connectivity vs. network measures

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
3 2:Visual_2 modularity_weighted 0.3812228 4.034720 0.0000547 0.0000000 1.0000000 2 1 84 0.0001874
4 2:Visual_2 efficiency_weighted 0.6803233 8.672584 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
5 3:Fronto_Parietal modularity_weighted 0.5633428 6.067067 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
6 3:Fronto_Parietal efficiency_weighted 0.5483251 6.066140 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
12 7:Ventral_Attention efficiency_weighted 0.2435168 2.320327 0.0203232 0.0000000 1.0000000 2 1 84 0.0487756
14 8:Salience efficiency_weighted 0.0809500 2.276849 0.0227952 -0.0315135 0.9748600 1 1 84 0.0497351
16 9:Cingulo_opercular efficiency_weighted 0.4369009 4.966279 0.0000007 -0.0065763 0.9947529 1 1 84 0.0000033
17 10:Somatomotor modularity_weighted 0.4344999 4.421424 0.0000098 0.0000000 1.0000000 1 1 84 0.0000392
18 10:Somatomotor efficiency_weighted 0.6143939 7.411538 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
20 11.5:Fronto_Parietal_2 efficiency_weighted 0.0778201 2.197850 0.0279598 -0.0385188 0.9692740 1 1 84 0.0559196
22 15:Medial_Parietal efficiency_weighted 0.1811223 2.706853 0.0067924 -0.0449929 0.9641130 1 1 84 0.0181131
23 16:Parieto_Occipital modularity_weighted -0.2858551 -2.733984 0.0062573 0.0000000 1.0000000 1 1 84 0.0181131

between-network connectivity vs. network measures

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
23 2_Visual_2-3_Frontoparietal_1 modularity_weighted -0.4244706 -4.503474 0.0000067 0.0000000 1.0000000 2 1 84 0.0000806
24 2_Visual_2-3_Frontoparietal_1 efficiency_weighted -0.6047674 -6.941670 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
29 2_Visual_2-7_Ventral_Attention modularity_weighted 0.3321868 3.227836 0.0012473 0.0000000 1.0000000 1 1 84 0.0071584
30 2_Visual_2-7_Ventral_Attention efficiency_weighted 0.5862106 6.631452 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
34 2_Visual_2-9_Cingulo_opercular efficiency_weighted 0.2904243 2.828435 0.0046776 0.0000000 1.0000000 2 1 84 0.0220517
35 2_Visual_2-10_Somatomotor modularity_weighted 0.4300484 4.657622 0.0000032 0.0000000 1.0000000 2 1 84 0.0000520
36 2_Visual_2-10_Somatomotor efficiency_weighted 0.6617557 8.427869 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
37 2_Visual_2-11.5_Frontoparietal_2 modularity_weighted -0.3513096 -4.035704 0.0000544 0.0000000 1.0000000 2 1 84 0.0005133
38 2_Visual_2-11.5_Frontoparietal_2 efficiency_weighted -0.3515671 -3.545687 0.0003916 0.0000000 1.0000000 2 1 84 0.0024614
39 2_Visual_2-15_Medial_Parietal modularity_weighted -0.3720569 -3.673688 0.0002391 0.0000000 1.0000000 1 1 84 0.0016360
40 2_Visual_2-15_Medial_Parietal efficiency_weighted -0.4239686 -2.389679 0.0168631 -0.0514571 0.9589613 1 1 84 0.0674525
42 2_Visual_2-16_Parieto_occipital efficiency_weighted 0.3055794 2.913460 0.0035745 0.0000000 1.0000000 2 1 84 0.0181474
47 3_Frontoparietal_1-7_Ventral_Attention modularity_weighted -0.3915958 -3.900538 0.0000960 0.0000000 1.0000000 1 1 84 0.0008446
48 3_Frontoparietal_1-7_Ventral_Attention efficiency_weighted -0.3515106 -3.463921 0.0005324 0.0000000 1.0000000 2 1 84 0.0031942
51 3_Frontoparietal_1-9_Cingulo_opercular modularity_weighted -0.2789326 -2.662114 0.0077652 0.0000000 1.0000000 1 1 84 0.0353449
52 3_Frontoparietal_1-9_Cingulo_opercular efficiency_weighted -0.4241296 -2.949723 0.0031806 -0.0258543 0.9793736 1 1 84 0.0171623
53 3_Frontoparietal_1-10_Somatomotor modularity_weighted -0.4632983 -5.219544 0.0000002 0.0000000 1.0000000 2 1 84 0.0000039
54 3_Frontoparietal_1-10_Somatomotor efficiency_weighted -0.5960823 -6.761144 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
55 3_Frontoparietal_1-11.5_Frontoparietal_2 modularity_weighted 0.2020673 2.365064 0.0180270 0.0000000 1.0000000 2 1 84 0.0699870
57 3_Frontoparietal_1-15_Medial_Parietal modularity_weighted 0.3760394 3.719448 0.0001997 0.0000000 1.0000000 1 1 84 0.0014642
64 4.5_Visual_1-7_Ventral_Attention efficiency_weighted -0.2329080 -4.636355 0.0000035 -0.0241638 0.9807220 1 1 84 0.0000520
67 4.5_Visual_1-9_Cingulo_opercular modularity_weighted 0.2999160 2.881417 0.0039589 0.0000000 1.0000000 1 1 84 0.0193547
70 4.5_Visual_1-10_Somatomotor efficiency_weighted -0.0630918 -3.848617 0.0001188 -0.0230462 0.9816134 1 1 84 0.0009800
94 7_Ventral_Attention-9_Cingulo_opercular efficiency_weighted 0.3664779 3.664435 0.0002479 0.0000000 1.0000000 2 1 84 0.0016360
95 7_Ventral_Attention-10_Somatomotor modularity_weighted 0.3820056 3.788451 0.0001516 0.0000000 1.0000000 1 1 84 0.0011770
96 7_Ventral_Attention-10_Somatomotor efficiency_weighted 0.5778562 6.468750 0.0000000 0.0000000 1.0000000 2 1 84 0.0000000
99 7_Ventral_Attention-15_Medial_Parietal modularity_weighted -0.2577257 -2.444679 0.0144981 0.0000000 1.0000000 1 1 84 0.0598048
101 7_Ventral_Attention-16_Parieto_occipital modularity_weighted 0.2658693 2.527704 0.0114811 0.0000000 1.0000000 1 1 84 0.0488873
105 8_Salience-10_Somatomotor modularity_weighted -0.2410508 -2.276390 0.0228227 0.0000000 1.0000000 1 1 84 0.0860742
106 8_Salience-10_Somatomotor efficiency_weighted -0.2645234 -2.581237 0.0098447 0.0000000 1.0000000 2 1 84 0.0433167
121 10_Somatomotor-11.5_Frontoparietal_2 modularity_weighted -0.3887592 -4.093037 0.0000426 0.0000000 1.0000000 2 1 84 0.0004323
122 10_Somatomotor-11.5_Frontoparietal_2 efficiency_weighted -0.4185697 -4.502416 0.0000067 0.0000000 1.0000000 2 1 84 0.0000806
123 10_Somatomotor-15_Medial_Parietal modularity_weighted -0.4239820 -4.290583 0.0000178 0.0000000 1.0000000 1 1 84 0.0001960
124 10_Somatomotor-15_Medial_Parietal efficiency_weighted -0.5166375 -4.844774 0.0000013 -0.0729446 0.9418502 1 1 84 0.0000239
129 11.5_Frontoparietal_2-16_Parieto_occipital modularity_weighted -0.3057329 -2.943004 0.0032504 0.0000000 1.0000000 1 1 84 0.0171623

network measures

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
modularity_weighted efficiency_weighted 0.5592778 7.209318 0 -0.0072301 0.9942313 1 1 84 0
efficiency_weighted modularity_weighted 0.5592778 6.398011 0 0.0000000 1.0000000 2 1 84 0

food vs. within-network connectivity

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
NA NA NA NA NA NA NA NA NA NA NA NA

food vs. behavior

Remove food variables that have too many zeros or ones, otherwise will fail

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
204 eggs afterscan.pulse -0.3542968 -3.527228 0.0004199 0.0000000 1.0000000 2 1 69 0.0585810
234 guacamole email.LIWCposemo -0.3177742 -3.942108 0.0000808 0.0000000 1.0000000 3 1 81 0.0226241
385 red_peppers afterscan.systolic 0.1577639 3.941155 0.0000811 -0.0840385 0.9330259 2 1 81 0.0226241
545 yogurt afterscan.diastolic 0.3843703 3.677852 0.0002352 -0.0466912 0.9627593 2 1 81 0.0437484

compare head motion to other measures

FD vs. behavior

[1] “no significant results”

FD vs. RNA-seq

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
31 V1 ME31:no enrichment -0.3389084 -3.379957 0.0007250 0 1 4 2 39 0.0228366
48 V1 ME48:Signaling in Immune system -0.5082077 -3.721216 0.0001983 0 1 1 1 39 0.0124908

FD vs. metabolites

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
11 V1 C11:amino acid/neurotransmitter transporters 0.4279585 2.957069 0.0031058 0 1 1 1 39 0.0465868

FD vs. wincorr

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
4 V1 4.5:Visual_1 -0.3347788 -3.249181 0.0011574 0 1 2 1 84 0.0138885
12 V1 16:Parieto_Occipital -0.2897112 -2.869529 0.0041108 0 1 2 1 84 0.0246650

FD vs. netdat

[1] “no significant results”

RNA-seq

RNA-seq vs. metabolism

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
75 ME5:ncRNA processing C15:no enrichment -0.4351396 -3.348350 0.0008129 0 1 1 1 48 0.0977296
165 ME11:Circadian clock system C15:no enrichment -0.4341470 -3.338936 0.0008410 0 1 1 1 48 0.0977296
255 ME17:no enrichment C15:no enrichment -0.4822142 -3.813549 0.0001370 0 1 1 1 48 0.0513746
265 ME18:no enrichment C10:Glycerophospholipid Biosynthesis 0.1538804 3.336630 0.0008480 0 1 1 1 48 0.0977296
270 ME18:no enrichment C15:no enrichment -0.4653446 -3.642400 0.0002701 0 1 1 1 48 0.0638130
445 ME30:Signalling by NGF C10:Glycerophospholipid Biosynthesis 0.2734568 4.081775 0.0000447 0 1 1 1 48 0.0422350
452 ME31:no enrichment C2:Glycerophospholipid Biosynthesis -0.4482704 -3.474337 0.0005121 0 1 1 1 48 0.0967900
555 ME37:IFN alpha signaling pathway C15:no enrichment -0.4311564 -3.310661 0.0009308 0 1 1 1 48 0.0977296
895 ME60:no enrichment C10:Glycerophospholipid Biosynthesis -0.2141123 -3.770235 0.0001631 0 1 1 1 48 0.0513746

RNA-seq vs. metabolism (full set)

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
632 ME6:Signaling in Immune system 2-hydroxyvaleric acid -0.3421003 -3.879714 0.0001046 0 1 2 2 48 0.0565973
NA NA NA NA NA NA NA NA NA NA NA NA
1644 ME16:no enrichment isothreonic acid -0.4043342 -4.281760 0.0000185 0 1 3 1 48 0.0176865
1699 ME17:no enrichment valine -0.4763322 -3.753270 0.0001745 0 1 1 1 48 0.0661678
1751 ME17:no enrichment isoleucine -0.5779081 -4.774554 0.0000018 0 1 2 1 48 0.0040086
1754 ME17:no enrichment indole-3-lactate -0.5732065 -4.846511 0.0000013 0 1 1 1 48 0.0040086
1793 ME17:no enrichment 3-hydroxybutyric acid -0.4702676 -3.691803 0.0002227 0 1 1 1 48 0.0743384
1794 ME17:no enrichment 3-hydroxybutanoic acid -0.4856296 -3.848857 0.0001187 0 1 1 1 48 0.0565973
1899 ME18:no enrichment 3-hydroxybutyric acid -0.4856997 -3.849584 0.0001183 0 1 1 1 48 0.0565973
1905 ME18:no enrichment 2-hydroxybutanoic acid -0.4633124 -3.622134 0.0002922 0 1 1 1 48 0.0829886
2317 ME22:no enrichment arachidonic acid 0.3329873 4.336761 0.0000145 0 1 5 2 48 0.0160913
2755 ME26:no enrichment 2-deoxyerythritol -0.4573886 -3.563469 0.0003660 0 1 1 1 48 0.0939879
2867 ME28:no enrichment uric acid 0.5021759 4.934424 0.0000008 0 1 2 1 48 0.0040086
3152 ME30:Signalling by NGF ethanolamine 0.4615186 3.604305 0.0003130 0 1 1 1 48 0.0835931
3249 ME31:no enrichment glycine -0.4532896 -3.523229 0.0004263 0 1 1 1 48 0.0958835
3323 ME32:no enrichment N-methylalanine 0.4627738 3.616775 0.0002983 0 1 1 1 48 0.0829886
3341 ME32:no enrichment isoleucine 0.4776140 3.766350 0.0001657 0 1 1 1 48 0.0661678
3470 ME33:no enrichment ethanolamine 0.4945473 3.942146 0.0000808 0 1 1 1 48 0.0565973
3501 ME34:no enrichment valine 0.4951803 3.948829 0.0000785 0 1 1 1 48 0.0565973
3553 ME34:no enrichment isoleucine 0.5385649 4.369136 0.0000125 0 1 2 1 48 0.0160913
3589 ME34:no enrichment arachidonic acid 0.4663038 3.651992 0.0002602 0 1 1 1 48 0.0827357
3596 ME34:no enrichment 3-hydroxybutanoic acid 0.4529029 3.519447 0.0004324 0 1 1 1 48 0.0958835
3919 ME37:IFN alpha signaling pathway 2-hydroxybutanoic acid -0.4525878 -3.516368 0.0004375 0 1 1 1 48 0.0958835
4161 ME40:no enrichment pelargonic acid 0.4638058 3.627047 0.0002867 0 1 1 1 48 0.0829886
4212 ME40:no enrichment ethanolamine 0.5309714 4.341180 0.0000142 0 1 1 1 48 0.0160913
4213 ME40:no enrichment erythritol 0.4511562 3.502397 0.0004611 0 1 1 1 48 0.0962097
4367 ME42:no enrichment pyrophosphate 0.2798297 3.734235 0.0001883 0 1 3 1 48 0.0661678
4828 ME46:no enrichment indole-3-lactate 0.5230285 3.734385 0.0001882 0 1 1 2 48 0.0661678
5166 ME49:no enrichment ethanolamine 0.4793094 3.783698 0.0001545 0 1 1 1 48 0.0661678
5248 ME50:transition metal ion binding isothreonic acid -0.3477173 -3.541926 0.0003972 0 1 3 1 48 0.0958835
5511 ME52:protein catabolic process 2-deoxyerythritol -0.4919710 -3.915029 0.0000904 0 1 1 1 48 0.0565973
6120 ME58:transcription ethanolamine -0.4885163 -3.878879 0.0001049 0 1 1 1 48 0.0565973
6363 ME61:no enrichment valine 0.3784238 3.511749 0.0004452 0 1 4 2 48 0.0958835

RNA-seq vs. food

xvar yvar cor.val t.arima arima.p t.drift drift.p AR MA nobs pval_bh
51 almonds ME51:no enrichment -0.3858545 -4.741886 0.0000021 0 1 2 2 39 0.0005907
212 beef ME23:Signaling by Wnt 0.2039302 3.560136 0.0003707 0 1 1 1 39 0.0361952
239 beef ME50:transition metal ion binding 0.2980454 4.019654 0.0000583 0 1 4 1 39 0.0103480
254 beets ME2:HIV Infection 0.1905025 3.347905 0.0008142 0 1 3 1 39 0.0757252
293 beets ME41:Axon guidance mediated by netrin 0.0113417 3.871408 0.0001082 0 1 3 2 39 0.0132082
336 blackberries ME21:negative regulation of macromolecule metabolic process 0.3467770 3.897050 0.0000974 0 1 1 2 39 0.0132082
439 brussels_sprouts ME61:no enrichment 0.5483022 4.328881 0.0000150 0 1 1 2 39 0.0032522
674 chocolate ME44:no enrichment -0.3766598 -3.693712 0.0002210 0 1 2 1 39 0.0227169
885 lamb ME3:Cell Cycle -0.2781618 -3.874810 0.0001067 0 1 3 1 39 0.0132082
986 lettuce ME41:Axon guidance mediated by netrin -0.1126209 -4.935004 0.0000008 0 1 4 1 39 0.0002609
1017 olives ME9:DNA repair -0.4107145 -3.742087 0.0001825 0 1 2 2 39 0.0209659
1018 olives ME10:Processing of Capped Intron-Containing Pre-mRNA -0.4098896 -3.303085 0.0009563 0 1 2 1 39 0.0829175
1024 olives ME16:no enrichment 0.4635820 5.875474 0.0000000 0 1 3 1 39 0.0000016
1042 olives ME34:no enrichment -0.2471633 -3.712263 0.0002054 0 1 1 1 39 0.0222875
1066 olives ME58:transcription 0.3576166 3.952304 0.0000774 0 1 1 1 39 0.0116289
1188 pork ME54:establishment of protein localization -0.3323935 -3.952291 0.0000774 0 1 1 3 39 0.0116289
1238 radishes ME41:Axon guidance mediated by netrin 0.1238205 4.578951 0.0000047 0 1 4 1 39 0.0011408
1306 rasberries ME46:no enrichment -0.3451855 -3.237392 0.0012063 0 1 4 2 39 0.0942343
1438 salad_dressing ME52:protein catabolic process 0.2153495 7.735617 0.0000000 0 1 3 3 39 0.0000000
1742 spinach ME41:Axon guidance mediated by netrin 0.0484442 9.027597 0.0000000 0 1 5 1 39 0.0000000
1743 spinach ME42:no enrichment -0.4621410 -3.297211 0.0009765 0 1 1 1 39 0.0829175
1842 tuna ME15:no enrichment -0.2140051 -6.341105 0.0000000 0 1 6 2 39 0.0000001
1868 tuna ME41:Axon guidance mediated by netrin 0.1998599 6.216184 0.0000000 0 1 4 1 39 0.0000002
1873 tuna ME46:no enrichment 0.3521372 4.179099 0.0000293 0 1 1 2 39 0.0057158
1888 tuna ME61:no enrichment 0.3861364 3.245986 0.0011704 0 1 1 2 39 0.0942343